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Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis

Background: Dysphagia in neurologically impaired children is associated with feeding difficulties, malnutrition and aspiration pneumonia. Esophageal high-resolution manometry (HRM) has been used in the diagnosis of motility disorders affecting the swallowing process. The aim of this study was to ana...

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Autores principales: Caruso, Anna Maria, Bommarito, Denisia, Girgenti, Vincenza, Amato, Glenda, Figuccia, Adele, Casuccio, Alessandra, Ferlisi, Annalisa, Genuardi, Rosaria, La Fata, Sabrina, Mattei, Rosalia, Milazzo, Mario Pietro Marcello, Di Pace, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777053/
https://www.ncbi.nlm.nih.gov/pubmed/36553430
http://dx.doi.org/10.3390/children9121987
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author Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Figuccia, Adele
Casuccio, Alessandra
Ferlisi, Annalisa
Genuardi, Rosaria
La Fata, Sabrina
Mattei, Rosalia
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
author_facet Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Figuccia, Adele
Casuccio, Alessandra
Ferlisi, Annalisa
Genuardi, Rosaria
La Fata, Sabrina
Mattei, Rosalia
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
author_sort Caruso, Anna Maria
collection PubMed
description Background: Dysphagia in neurologically impaired children is associated with feeding difficulties, malnutrition and aspiration pneumonia. Esophageal high-resolution manometry (HRM) has been used in the diagnosis of motility disorders affecting the swallowing process. The aim of this study was to analyze swallowing functions in NI children by using HRM in order to establish swallow parameters identifying inhalation risk. Methods: Twenty-five NI children with cerebral palsy were submitted to esophageal HRM with UES analysis, comparing the results with non-NI children. The following parameters were evaluated: maximum pressure and duration of contraction of the velopharynx (VP) and tongue base (TB), and maximal, minimal, resting pressure and relaxation duration of the upper esophageal sphincter (UES). Results: pVP max, pTB max, pUES max and resting pressure were lower, while p UES minimal was higher and relaxation duration was shorter in NI children vs. the control group. Predictive values of inhalation risk were evaluated. Conclusions: This study evaluates inhalation risk in NI children using HRM to study UES function. Our results confirm the alterations described in NI children: insufficient contraction and clearing force for bolus transmission through the pharynx and incomplete UES relaxation can predispose to pharyngeal residues and inhalation independently of swallowing because of lower values of UES resting.
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spelling pubmed-97770532022-12-23 Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis Caruso, Anna Maria Bommarito, Denisia Girgenti, Vincenza Amato, Glenda Figuccia, Adele Casuccio, Alessandra Ferlisi, Annalisa Genuardi, Rosaria La Fata, Sabrina Mattei, Rosalia Milazzo, Mario Pietro Marcello Di Pace, Maria Rita Children (Basel) Article Background: Dysphagia in neurologically impaired children is associated with feeding difficulties, malnutrition and aspiration pneumonia. Esophageal high-resolution manometry (HRM) has been used in the diagnosis of motility disorders affecting the swallowing process. The aim of this study was to analyze swallowing functions in NI children by using HRM in order to establish swallow parameters identifying inhalation risk. Methods: Twenty-five NI children with cerebral palsy were submitted to esophageal HRM with UES analysis, comparing the results with non-NI children. The following parameters were evaluated: maximum pressure and duration of contraction of the velopharynx (VP) and tongue base (TB), and maximal, minimal, resting pressure and relaxation duration of the upper esophageal sphincter (UES). Results: pVP max, pTB max, pUES max and resting pressure were lower, while p UES minimal was higher and relaxation duration was shorter in NI children vs. the control group. Predictive values of inhalation risk were evaluated. Conclusions: This study evaluates inhalation risk in NI children using HRM to study UES function. Our results confirm the alterations described in NI children: insufficient contraction and clearing force for bolus transmission through the pharynx and incomplete UES relaxation can predispose to pharyngeal residues and inhalation independently of swallowing because of lower values of UES resting. MDPI 2022-12-17 /pmc/articles/PMC9777053/ /pubmed/36553430 http://dx.doi.org/10.3390/children9121987 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Caruso, Anna Maria
Bommarito, Denisia
Girgenti, Vincenza
Amato, Glenda
Figuccia, Adele
Casuccio, Alessandra
Ferlisi, Annalisa
Genuardi, Rosaria
La Fata, Sabrina
Mattei, Rosalia
Milazzo, Mario Pietro Marcello
Di Pace, Maria Rita
Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title_full Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title_fullStr Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title_full_unstemmed Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title_short Evaluation of Dysphagia and Inhalation Risk in Neurologically Impaired Children Using Esophageal High-Resolution Manometry with Swallowing Analysis
title_sort evaluation of dysphagia and inhalation risk in neurologically impaired children using esophageal high-resolution manometry with swallowing analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777053/
https://www.ncbi.nlm.nih.gov/pubmed/36553430
http://dx.doi.org/10.3390/children9121987
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