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The Challenge of Dimethyl Fumarate Repurposing in Eye Pathologies
Dimethyl fumarate (DMF) is a small molecule currently approved and used in the treatment of psoriasis and multiple sclerosis due to its immuno-modulatory, anti-inflammatory, and antioxidant properties. As an Nrf2 activator through Keap1 protein inhibition, DMF unveils a potential therapeutical use t...
Autores principales: | Manai, Federico, Govoni, Stefano, Amadio, Marialaura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777082/ https://www.ncbi.nlm.nih.gov/pubmed/36552824 http://dx.doi.org/10.3390/cells11244061 |
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