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The Challenge of Dimethyl Fumarate Repurposing in Eye Pathologies

Dimethyl fumarate (DMF) is a small molecule currently approved and used in the treatment of psoriasis and multiple sclerosis due to its immuno-modulatory, anti-inflammatory, and antioxidant properties. As an Nrf2 activator through Keap1 protein inhibition, DMF unveils a potential therapeutical use t...

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Detalles Bibliográficos
Autores principales: Manai, Federico, Govoni, Stefano, Amadio, Marialaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777082/
https://www.ncbi.nlm.nih.gov/pubmed/36552824
http://dx.doi.org/10.3390/cells11244061

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