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Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs

Glaucoma is an eye disease that gradually deteriorates vision. Much research focuses on extracting information from the optic disc and optic cup, the structure used for measuring the cup-to-disc ratio. These structures are commonly segmented with deeplearning techniques, primarily using Encoder–Deco...

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Autores principales: Alfonso-Francia, Gendry, Pedraza-Ortega, Jesus Carlos, Badillo-Fernández, Mariana, Toledano-Ayala, Manuel, Aceves-Fernandez, Marco Antonio, Rodriguez-Resendiz, Juvenal, Ko, Seok-Bum, Tovar-Arriaga, Saul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777130/
https://www.ncbi.nlm.nih.gov/pubmed/36553037
http://dx.doi.org/10.3390/diagnostics12123031
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author Alfonso-Francia, Gendry
Pedraza-Ortega, Jesus Carlos
Badillo-Fernández, Mariana
Toledano-Ayala, Manuel
Aceves-Fernandez, Marco Antonio
Rodriguez-Resendiz, Juvenal
Ko, Seok-Bum
Tovar-Arriaga, Saul
author_facet Alfonso-Francia, Gendry
Pedraza-Ortega, Jesus Carlos
Badillo-Fernández, Mariana
Toledano-Ayala, Manuel
Aceves-Fernandez, Marco Antonio
Rodriguez-Resendiz, Juvenal
Ko, Seok-Bum
Tovar-Arriaga, Saul
author_sort Alfonso-Francia, Gendry
collection PubMed
description Glaucoma is an eye disease that gradually deteriorates vision. Much research focuses on extracting information from the optic disc and optic cup, the structure used for measuring the cup-to-disc ratio. These structures are commonly segmented with deeplearning techniques, primarily using Encoder–Decoder models, which are hard to train and time-consuming. Object detection models using convolutional neural networks can extract features from fundus retinal images with good precision. However, the superiority of one model over another for a specific task is still being determined. The main goal of our approach is to compare object detection model performance to automate segment cups and discs on fundus images. This study brings the novelty of seeing the behavior of different object detection models in the detection and segmentation of the disc and the optical cup (Mask R-CNN, MS R-CNN, CARAFE, Cascade Mask R-CNN, GCNet, SOLO, Point_Rend), evaluated on Retinal Fundus Images for Glaucoma Analysis (REFUGE), and G1020 datasets. Reported metrics were Average Precision (AP), F1-score, IoU, and AUCPR. Several models achieved the highest AP with a perfect 1.000 when the threshold for IoU was set up at 0.50 on REFUGE, and the lowest was Cascade Mask R-CNN with an AP of 0.997. On the G1020 dataset, the best model was Point_Rend with an AP of 0.956, and the worst was SOLO with 0.906. It was concluded that the methods reviewed achieved excellent performance with high precision and recall values, showing efficiency and effectiveness. The problem of how many images are needed was addressed with an initial value of 100, with excellent results. Data augmentation, multi-scale handling, and anchor box size brought improvements. The capability to translate knowledge from one database to another shows promising results too.
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spelling pubmed-97771302022-12-23 Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs Alfonso-Francia, Gendry Pedraza-Ortega, Jesus Carlos Badillo-Fernández, Mariana Toledano-Ayala, Manuel Aceves-Fernandez, Marco Antonio Rodriguez-Resendiz, Juvenal Ko, Seok-Bum Tovar-Arriaga, Saul Diagnostics (Basel) Article Glaucoma is an eye disease that gradually deteriorates vision. Much research focuses on extracting information from the optic disc and optic cup, the structure used for measuring the cup-to-disc ratio. These structures are commonly segmented with deeplearning techniques, primarily using Encoder–Decoder models, which are hard to train and time-consuming. Object detection models using convolutional neural networks can extract features from fundus retinal images with good precision. However, the superiority of one model over another for a specific task is still being determined. The main goal of our approach is to compare object detection model performance to automate segment cups and discs on fundus images. This study brings the novelty of seeing the behavior of different object detection models in the detection and segmentation of the disc and the optical cup (Mask R-CNN, MS R-CNN, CARAFE, Cascade Mask R-CNN, GCNet, SOLO, Point_Rend), evaluated on Retinal Fundus Images for Glaucoma Analysis (REFUGE), and G1020 datasets. Reported metrics were Average Precision (AP), F1-score, IoU, and AUCPR. Several models achieved the highest AP with a perfect 1.000 when the threshold for IoU was set up at 0.50 on REFUGE, and the lowest was Cascade Mask R-CNN with an AP of 0.997. On the G1020 dataset, the best model was Point_Rend with an AP of 0.956, and the worst was SOLO with 0.906. It was concluded that the methods reviewed achieved excellent performance with high precision and recall values, showing efficiency and effectiveness. The problem of how many images are needed was addressed with an initial value of 100, with excellent results. Data augmentation, multi-scale handling, and anchor box size brought improvements. The capability to translate knowledge from one database to another shows promising results too. MDPI 2022-12-02 /pmc/articles/PMC9777130/ /pubmed/36553037 http://dx.doi.org/10.3390/diagnostics12123031 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alfonso-Francia, Gendry
Pedraza-Ortega, Jesus Carlos
Badillo-Fernández, Mariana
Toledano-Ayala, Manuel
Aceves-Fernandez, Marco Antonio
Rodriguez-Resendiz, Juvenal
Ko, Seok-Bum
Tovar-Arriaga, Saul
Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title_full Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title_fullStr Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title_full_unstemmed Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title_short Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs
title_sort performance evaluation of different object detection models for the segmentation of optical cups and discs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777130/
https://www.ncbi.nlm.nih.gov/pubmed/36553037
http://dx.doi.org/10.3390/diagnostics12123031
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