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Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss

Peroxisome Biogenesis Disorders (PBD) and Zellweger syndrome spectrum disorders (ZSD) are rare genetic multisystem disorders that include hearing impairment and are associated with defects in peroxisome assembly, function, or both. Mutations in 13 peroxin (PEX) genes have been found to cause PBD-ZSD...

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Detalles Bibliográficos
Autores principales:	Mauriac, Stephanie A., Peineau, Thibault, Zuberi, Aamir, Lutz, Cathleen, Géléoc, Gwénaëlle S. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777190/ https://www.ncbi.nlm.nih.gov/pubmed/36552747 http://dx.doi.org/10.3390/cells11243982

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