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Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction

Introduction: The timing of contralateral symmetrisation in patients with large and ptotic breasts undergoing a unilateral skin-reducing mastectomy (SRM) is one of the most debated topics in the reconstructive field. There is no evidence to support the advantage of immediate or delayed symmetrisatio...

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Autores principales: Casella, Donato, Fusario, Daniele, Cassetti, Dario, Pesce, Anna Lisa, De Luca, Alessandro, Guerra, Maristella, Cuomo, Roberto, Ribuffo, Diego, Neri, Alessandro, Marcasciano, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777212/
https://www.ncbi.nlm.nih.gov/pubmed/36547151
http://dx.doi.org/10.3390/curroncol29120737
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author Casella, Donato
Fusario, Daniele
Cassetti, Dario
Pesce, Anna Lisa
De Luca, Alessandro
Guerra, Maristella
Cuomo, Roberto
Ribuffo, Diego
Neri, Alessandro
Marcasciano, Marco
author_facet Casella, Donato
Fusario, Daniele
Cassetti, Dario
Pesce, Anna Lisa
De Luca, Alessandro
Guerra, Maristella
Cuomo, Roberto
Ribuffo, Diego
Neri, Alessandro
Marcasciano, Marco
author_sort Casella, Donato
collection PubMed
description Introduction: The timing of contralateral symmetrisation in patients with large and ptotic breasts undergoing a unilateral skin-reducing mastectomy (SRM) is one of the most debated topics in the reconstructive field. There is no evidence to support the advantage of immediate or delayed symmetrisation to help surgeons with this decision. The aim of this study was to investigate the clinical and aesthetic outcomes of immediate symmetrisation. Methods: A randomised observational study was conducted on patients who underwent an SRM for unilateral breast cancer. Based on a simple randomisation list, patients were divided into two groups: a delayed symmetrisation group versus an immediate symmetrisation group. The postoperative complications, BREAST-Q outcomes and reoperations were compared. Results: Out of a total of 84 patients undergoing an SRM between January 2018 and January 2021, 42 patients underwent immediate symmetrisation and 42 patients had delayed symmetrisation. Three implant losses (7.2%) were observed and we reported three wound dehiscences; one of these was in a contralateral breast reconstruction in the immediate symmetrisation group. The BREAST-Q patient-reported outcome measures recorded better aesthetic outcomes and a high patient satisfaction for the immediate symmetrisation group. Conclusions: Simultaneous controlateral symmetrisation is a good alternative to achieve better satisfaction and quality of life for patients; from a surgical point of view, it does not excessively impact on the second time of reconstruction.
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spelling pubmed-97772122022-12-23 Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction Casella, Donato Fusario, Daniele Cassetti, Dario Pesce, Anna Lisa De Luca, Alessandro Guerra, Maristella Cuomo, Roberto Ribuffo, Diego Neri, Alessandro Marcasciano, Marco Curr Oncol Article Introduction: The timing of contralateral symmetrisation in patients with large and ptotic breasts undergoing a unilateral skin-reducing mastectomy (SRM) is one of the most debated topics in the reconstructive field. There is no evidence to support the advantage of immediate or delayed symmetrisation to help surgeons with this decision. The aim of this study was to investigate the clinical and aesthetic outcomes of immediate symmetrisation. Methods: A randomised observational study was conducted on patients who underwent an SRM for unilateral breast cancer. Based on a simple randomisation list, patients were divided into two groups: a delayed symmetrisation group versus an immediate symmetrisation group. The postoperative complications, BREAST-Q outcomes and reoperations were compared. Results: Out of a total of 84 patients undergoing an SRM between January 2018 and January 2021, 42 patients underwent immediate symmetrisation and 42 patients had delayed symmetrisation. Three implant losses (7.2%) were observed and we reported three wound dehiscences; one of these was in a contralateral breast reconstruction in the immediate symmetrisation group. The BREAST-Q patient-reported outcome measures recorded better aesthetic outcomes and a high patient satisfaction for the immediate symmetrisation group. Conclusions: Simultaneous controlateral symmetrisation is a good alternative to achieve better satisfaction and quality of life for patients; from a surgical point of view, it does not excessively impact on the second time of reconstruction. MDPI 2022-11-30 /pmc/articles/PMC9777212/ /pubmed/36547151 http://dx.doi.org/10.3390/curroncol29120737 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Casella, Donato
Fusario, Daniele
Cassetti, Dario
Pesce, Anna Lisa
De Luca, Alessandro
Guerra, Maristella
Cuomo, Roberto
Ribuffo, Diego
Neri, Alessandro
Marcasciano, Marco
Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title_full Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title_fullStr Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title_full_unstemmed Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title_short Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction
title_sort controlateral symmetrisation in srm for breast cancer: now or then? immediate versus delayed symmetrisation in a two-stage breast reconstruction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777212/
https://www.ncbi.nlm.nih.gov/pubmed/36547151
http://dx.doi.org/10.3390/curroncol29120737
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