tRNA-like Transcripts from the NEAT1-MALAT1 Genomic Region Critically Influence Human Innate Immunity and Macrophage Functions

The evolutionary conserved NEAT1-MALAT1 gene cluster generates large noncoding transcripts remaining nuclear, while tRNA-like transcripts (mascRNA, menRNA) enzymatically generated from these precursors translocate to the cytosol. Whereas functions have been assigned to the nuclear transcripts, data...

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Detalles Bibliográficos
Autores principales: Gast, Martina, Nageswaran, Vanasa, Kuss, Andreas W., Tzvetkova, Ana, Wang, Xiaomin, Mochmann, Liliana H., Rad, Pegah Ramezani, Weiss, Stefan, Simm, Stefan, Zeller, Tanja, Voelzke, Henry, Hoffmann, Wolfgang, Völker, Uwe, Felix, Stefan B., Dörr, Marcus, Beling, Antje, Skurk, Carsten, Leistner, David-Manuel, Rauch, Bernhard H., Hirose, Tetsuro, Heidecker, Bettina, Klingel, Karin, Nakagawa, Shinichi, Poller, Wolfram C., Swirski, Filip K., Haghikia, Arash, Poller, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777231/
https://www.ncbi.nlm.nih.gov/pubmed/36552736
http://dx.doi.org/10.3390/cells11243970

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