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Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification

A person infected with drug-resistant tuberculosis (DR-TB) is the one who does not respond to typical TB treatment. DR-TB necessitates a longer treatment period and a more difficult treatment protocol. In addition, it can spread and infect individuals in the same manner as regular TB, despite the fa...

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Autores principales: Prasitpuriprecha, Chutinun, Pitakaso, Rapeepan, Gonwirat, Sarayut, Enkvetchakul, Prem, Preeprem, Thanawadee, Jantama, Sirima Suvarnakuta, Kaewta, Chutchai, Weerayuth, Nantawatana, Srichok, Thanatkij, Khonjun, Surajet, Nanthasamroeng, Natthapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777254/
https://www.ncbi.nlm.nih.gov/pubmed/36552987
http://dx.doi.org/10.3390/diagnostics12122980
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author Prasitpuriprecha, Chutinun
Pitakaso, Rapeepan
Gonwirat, Sarayut
Enkvetchakul, Prem
Preeprem, Thanawadee
Jantama, Sirima Suvarnakuta
Kaewta, Chutchai
Weerayuth, Nantawatana
Srichok, Thanatkij
Khonjun, Surajet
Nanthasamroeng, Natthapong
author_facet Prasitpuriprecha, Chutinun
Pitakaso, Rapeepan
Gonwirat, Sarayut
Enkvetchakul, Prem
Preeprem, Thanawadee
Jantama, Sirima Suvarnakuta
Kaewta, Chutchai
Weerayuth, Nantawatana
Srichok, Thanatkij
Khonjun, Surajet
Nanthasamroeng, Natthapong
author_sort Prasitpuriprecha, Chutinun
collection PubMed
description A person infected with drug-resistant tuberculosis (DR-TB) is the one who does not respond to typical TB treatment. DR-TB necessitates a longer treatment period and a more difficult treatment protocol. In addition, it can spread and infect individuals in the same manner as regular TB, despite the fact that early detection of DR-TB could reduce the cost and length of TB treatment. This study provided a fast and effective classification scheme for the four subtypes of TB: Drug-sensitive tuberculosis (DS-TB), drug-resistant tuberculosis (DR-TB), multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB). The drug response classification system (DRCS) has been developed as a classification tool for DR-TB subtypes. As a classification method, ensemble deep learning (EDL) with two types of image preprocessing methods, four convolutional neural network (CNN) architectures, and three decision fusion methods have been created. Later, the model developed by EDL will be included in the dialog-based object query system (DBOQS), in order to enable the use of DRCS as the classification tool for DR-TB in assisting medical professionals with diagnosing DR-TB. EDL yields an improvement of 1.17–43.43% over the existing methods for classifying DR-TB, while compared with classic deep learning, it generates 31.25% more accuracy. DRCS was able to increase accuracy to 95.8% and user trust to 95.1%, and after the trial period, 99.70% of users were interested in continuing the utilization of the system as a supportive diagnostic tool.
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spelling pubmed-97772542022-12-23 Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification Prasitpuriprecha, Chutinun Pitakaso, Rapeepan Gonwirat, Sarayut Enkvetchakul, Prem Preeprem, Thanawadee Jantama, Sirima Suvarnakuta Kaewta, Chutchai Weerayuth, Nantawatana Srichok, Thanatkij Khonjun, Surajet Nanthasamroeng, Natthapong Diagnostics (Basel) Article A person infected with drug-resistant tuberculosis (DR-TB) is the one who does not respond to typical TB treatment. DR-TB necessitates a longer treatment period and a more difficult treatment protocol. In addition, it can spread and infect individuals in the same manner as regular TB, despite the fact that early detection of DR-TB could reduce the cost and length of TB treatment. This study provided a fast and effective classification scheme for the four subtypes of TB: Drug-sensitive tuberculosis (DS-TB), drug-resistant tuberculosis (DR-TB), multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB). The drug response classification system (DRCS) has been developed as a classification tool for DR-TB subtypes. As a classification method, ensemble deep learning (EDL) with two types of image preprocessing methods, four convolutional neural network (CNN) architectures, and three decision fusion methods have been created. Later, the model developed by EDL will be included in the dialog-based object query system (DBOQS), in order to enable the use of DRCS as the classification tool for DR-TB in assisting medical professionals with diagnosing DR-TB. EDL yields an improvement of 1.17–43.43% over the existing methods for classifying DR-TB, while compared with classic deep learning, it generates 31.25% more accuracy. DRCS was able to increase accuracy to 95.8% and user trust to 95.1%, and after the trial period, 99.70% of users were interested in continuing the utilization of the system as a supportive diagnostic tool. MDPI 2022-11-28 /pmc/articles/PMC9777254/ /pubmed/36552987 http://dx.doi.org/10.3390/diagnostics12122980 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Prasitpuriprecha, Chutinun
Pitakaso, Rapeepan
Gonwirat, Sarayut
Enkvetchakul, Prem
Preeprem, Thanawadee
Jantama, Sirima Suvarnakuta
Kaewta, Chutchai
Weerayuth, Nantawatana
Srichok, Thanatkij
Khonjun, Surajet
Nanthasamroeng, Natthapong
Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title_full Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title_fullStr Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title_full_unstemmed Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title_short Embedded AMIS-Deep Learning with Dialog-Based Object Query System for Multi-Class Tuberculosis Drug Response Classification
title_sort embedded amis-deep learning with dialog-based object query system for multi-class tuberculosis drug response classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777254/
https://www.ncbi.nlm.nih.gov/pubmed/36552987
http://dx.doi.org/10.3390/diagnostics12122980
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