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The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection
The endoplasmic reticulum chaperone BiP (also known as GRP-78 or HSPA5) maintains protein folding to allow cell proliferation and survival and has been implicated in carcinogenesis, tumor progression, and therapy resistance. BiP’s association with clinical factors and prognostic potential in breast...
Autores principales: | Direito, Inês, Gomes, Daniela, Monteiro, Fátima Liliana, Carneiro, Isa, Lobo, João, Henrique, Rui, Jerónimo, Carmen, Helguero, Luisa Alejandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777260/ https://www.ncbi.nlm.nih.gov/pubmed/36547124 http://dx.doi.org/10.3390/curroncol29120710 |
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