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CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca(2+) via Mitochondrial NCLX

Mitochondrial Ca(2+) efflux by NCLX is a critical rate-limiting step in mitochondria signaling. We previously showed that NCLX is phosphorylated at a putative Casein Kinase 2 (CKII) site, the serine 271 (S271). Here, we asked if NCLX is regulated by CKII and interrogated the physiological implicatio...

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Detalles Bibliográficos
Autores principales: Katoshevski, Tomer, Bar, Lior, Tikochinsky, Eliav, Harel, Shimon, Ben-Kasus Nissim, Tsipi, Bogeski, Ivan, Hershfinkel, Michal, Attali, Bernard, Sekler, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777275/
https://www.ncbi.nlm.nih.gov/pubmed/36552754
http://dx.doi.org/10.3390/cells11243990