SH3BP2 Silencing Increases miRNAs Targeting ETV1 and Microphthalmia-Associated Transcription Factor, Decreasing the Proliferation of Gastrointestinal Stromal Tumors

SIMPLE SUMMARY: A previous study showed that silencing the adaptor molecule SH3 Binding Protein 2 (SH3BP2) reduced oncogenic KIT and PDGFRA receptor levels and impaired gastrointestinal stromal tumor (GIST) growth. This study tries to get insights into the molecular mechanism underlying this effect....

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Detalles Bibliográficos
Autores principales: Proaño-Pérez, Elizabeth, Serrano-Candelas, Eva, Mancia, Cindy, Navinés-Ferrer, Arnau, Guerrero, Mario, Martin, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777313/
https://www.ncbi.nlm.nih.gov/pubmed/36551682
http://dx.doi.org/10.3390/cancers14246198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777313/
https://www.ncbi.nlm.nih.gov/pubmed/36551682
http://dx.doi.org/10.3390/cancers14246198

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