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Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis

Recent advancements in surgical and anti-cancer therapies have provided significant hope of long survival in patients with pancreatic cancer (PC). To realize this hope, routine medical checkups of asymptomatic people should be performed to identify operable PCs. In this study, we evaluated the effic...

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Autores principales: Yamaguchi, Atsushi, Kato, Naohiro, Sugata, Shuhei, Hamada, Takuro, Furuya, Nao, Mizumoto, Takeshi, Tamaru, Yuzuru, Kusunoki, Ryusaku, Kuwai, Toshio, Kouno, Hirotaka, Toyota, Naoyuki, Sudo, Takeshi, Kuraoka, Kazuya, Kohno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777348/
https://www.ncbi.nlm.nih.gov/pubmed/36552920
http://dx.doi.org/10.3390/diagnostics12122913
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author Yamaguchi, Atsushi
Kato, Naohiro
Sugata, Shuhei
Hamada, Takuro
Furuya, Nao
Mizumoto, Takeshi
Tamaru, Yuzuru
Kusunoki, Ryusaku
Kuwai, Toshio
Kouno, Hirotaka
Toyota, Naoyuki
Sudo, Takeshi
Kuraoka, Kazuya
Kohno, Hiroshi
author_facet Yamaguchi, Atsushi
Kato, Naohiro
Sugata, Shuhei
Hamada, Takuro
Furuya, Nao
Mizumoto, Takeshi
Tamaru, Yuzuru
Kusunoki, Ryusaku
Kuwai, Toshio
Kouno, Hirotaka
Toyota, Naoyuki
Sudo, Takeshi
Kuraoka, Kazuya
Kohno, Hiroshi
author_sort Yamaguchi, Atsushi
collection PubMed
description Recent advancements in surgical and anti-cancer therapies have provided significant hope of long survival in patients with pancreatic cancer (PC). To realize this hope, routine medical checkups of asymptomatic people should be performed to identify operable PCs. In this study, we evaluated the efficacy of medical checkups using abdominal ultrasonography (US). We retrospectively analyzed 374 patients with PC at our institute between 2010 and 2021. We divided these patients into several groups according to the diagnostic approach and compared their background and prognosis. These groups comprised PCs diagnosed through (a) symptoms, 242 cases; (b) US during medical checkup for asymptomatic individuals, 17; and other means. Of the 374 patients, 192 were men (51.3%), and the median age was 74 years (34–105). Tumors were located in the pancreatic tail in 67 patients (17.9%). Excision ratio and 5-year survival rate were significantly better in group (b) than in (a) (58.8% vs. 23.1%, p < 0.01 and 42.2% vs. 9.4%, p < 0.001, respectively). The prognosis of patients diagnosed using US during medical checkup was better than that of patients identified through symptomatic presentation of PC. US for asymptomatic individuals with PC might be one of the useful modalities for promoting better prognosis of PCs.
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spelling pubmed-97773482022-12-23 Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis Yamaguchi, Atsushi Kato, Naohiro Sugata, Shuhei Hamada, Takuro Furuya, Nao Mizumoto, Takeshi Tamaru, Yuzuru Kusunoki, Ryusaku Kuwai, Toshio Kouno, Hirotaka Toyota, Naoyuki Sudo, Takeshi Kuraoka, Kazuya Kohno, Hiroshi Diagnostics (Basel) Article Recent advancements in surgical and anti-cancer therapies have provided significant hope of long survival in patients with pancreatic cancer (PC). To realize this hope, routine medical checkups of asymptomatic people should be performed to identify operable PCs. In this study, we evaluated the efficacy of medical checkups using abdominal ultrasonography (US). We retrospectively analyzed 374 patients with PC at our institute between 2010 and 2021. We divided these patients into several groups according to the diagnostic approach and compared their background and prognosis. These groups comprised PCs diagnosed through (a) symptoms, 242 cases; (b) US during medical checkup for asymptomatic individuals, 17; and other means. Of the 374 patients, 192 were men (51.3%), and the median age was 74 years (34–105). Tumors were located in the pancreatic tail in 67 patients (17.9%). Excision ratio and 5-year survival rate were significantly better in group (b) than in (a) (58.8% vs. 23.1%, p < 0.01 and 42.2% vs. 9.4%, p < 0.001, respectively). The prognosis of patients diagnosed using US during medical checkup was better than that of patients identified through symptomatic presentation of PC. US for asymptomatic individuals with PC might be one of the useful modalities for promoting better prognosis of PCs. MDPI 2022-11-23 /pmc/articles/PMC9777348/ /pubmed/36552920 http://dx.doi.org/10.3390/diagnostics12122913 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yamaguchi, Atsushi
Kato, Naohiro
Sugata, Shuhei
Hamada, Takuro
Furuya, Nao
Mizumoto, Takeshi
Tamaru, Yuzuru
Kusunoki, Ryusaku
Kuwai, Toshio
Kouno, Hirotaka
Toyota, Naoyuki
Sudo, Takeshi
Kuraoka, Kazuya
Kohno, Hiroshi
Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title_full Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title_fullStr Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title_full_unstemmed Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title_short Effectiveness of Abdominal Ultrasonography for Improving the Prognosis of Pancreatic Cancer during Medical Checkup: A Single Center Retrospective Analysis
title_sort effectiveness of abdominal ultrasonography for improving the prognosis of pancreatic cancer during medical checkup: a single center retrospective analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777348/
https://www.ncbi.nlm.nih.gov/pubmed/36552920
http://dx.doi.org/10.3390/diagnostics12122913
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