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ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis

The fatal clinical course of human glioblastoma (GBM) despite aggressive adjuvant therapies is due to high rates of recurrent tumor growth driven by tumor cells with stem-cell characteristics (glioma stem cells, GSCs). The aldehyde dehydrogenase 1 (ALDH1) family of enzymes has been shown to be a bio...

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Detalles Bibliográficos
Autores principales:	Wu, Yang, Kram, Helena, Gempt, Jens, Liesche-Starnecker, Friederike, Wu, Wei, Schlegel, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777439/ https://www.ncbi.nlm.nih.gov/pubmed/36552781 http://dx.doi.org/10.3390/cells11244015

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