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Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?

Background: The aim of this study was to assess and compare the time in range (TIR) of children with type 1 diabetes (T1D) before and during a diabetes summer camp using different therapy modalities. Methods: A retrospective analysis of continuous glucose monitoring (CGM) data collected from 26 chil...

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Autores principales: Nagl, Katrin, Bozic, Ina, Berger, Gabriele, Tauschmann, Martin, Blauensteiner, Nicole, Weimann, Katharina, Mader, Julia K., Rami-Merhar, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777517/
https://www.ncbi.nlm.nih.gov/pubmed/36553394
http://dx.doi.org/10.3390/children9121951
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author Nagl, Katrin
Bozic, Ina
Berger, Gabriele
Tauschmann, Martin
Blauensteiner, Nicole
Weimann, Katharina
Mader, Julia K.
Rami-Merhar, Birgit
author_facet Nagl, Katrin
Bozic, Ina
Berger, Gabriele
Tauschmann, Martin
Blauensteiner, Nicole
Weimann, Katharina
Mader, Julia K.
Rami-Merhar, Birgit
author_sort Nagl, Katrin
collection PubMed
description Background: The aim of this study was to assess and compare the time in range (TIR) of children with type 1 diabetes (T1D) before and during a diabetes summer camp using different therapy modalities. Methods: A retrospective analysis of continuous glucose monitoring (CGM) data collected from 26 children with T1D (mean age: 11.0 ± 1.4 years; 62% female; 62% on insulin pump; Hb1Ac 7.3 ± 0.8% (56.3 ± 8.7 mmol/mol) before and during a 14-day summer camp. CGM methods: 50% intermittently scanned CGM (isCGM) and 50% real-time CGM (rtCGM). No child was using a hybrid closed loop system. Results: Mean TIR during camp was significantly higher than before camp ((67.0 ± 10.7%) vs. 58.2% ± 17.4%, p = 0.004). There was a significant reduction in time above range (TAR) (p = 0.001) and increase in time below range (TBR) (p < 0.001), Children using isCGM showed a more pronounced improvement in TIR during camp compared to rtCGM-users (p = 0.025). The increase in TIR strongly correlated with numbers of scans per day in isCGM-users (r = 0.751, p = 0.003). Compared to isCGM-users, rtCGM-users showed significantly less TBR. The TIR target was met by 30.8% of participants during camp. Conclusion: Glycemic control improved significantly during the camp. However, on average, the therapy goal (TIR > 70%) could not be achieved despite great professional effort.
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spelling pubmed-97775172022-12-23 Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect? Nagl, Katrin Bozic, Ina Berger, Gabriele Tauschmann, Martin Blauensteiner, Nicole Weimann, Katharina Mader, Julia K. Rami-Merhar, Birgit Children (Basel) Article Background: The aim of this study was to assess and compare the time in range (TIR) of children with type 1 diabetes (T1D) before and during a diabetes summer camp using different therapy modalities. Methods: A retrospective analysis of continuous glucose monitoring (CGM) data collected from 26 children with T1D (mean age: 11.0 ± 1.4 years; 62% female; 62% on insulin pump; Hb1Ac 7.3 ± 0.8% (56.3 ± 8.7 mmol/mol) before and during a 14-day summer camp. CGM methods: 50% intermittently scanned CGM (isCGM) and 50% real-time CGM (rtCGM). No child was using a hybrid closed loop system. Results: Mean TIR during camp was significantly higher than before camp ((67.0 ± 10.7%) vs. 58.2% ± 17.4%, p = 0.004). There was a significant reduction in time above range (TAR) (p = 0.001) and increase in time below range (TBR) (p < 0.001), Children using isCGM showed a more pronounced improvement in TIR during camp compared to rtCGM-users (p = 0.025). The increase in TIR strongly correlated with numbers of scans per day in isCGM-users (r = 0.751, p = 0.003). Compared to isCGM-users, rtCGM-users showed significantly less TBR. The TIR target was met by 30.8% of participants during camp. Conclusion: Glycemic control improved significantly during the camp. However, on average, the therapy goal (TIR > 70%) could not be achieved despite great professional effort. MDPI 2022-12-12 /pmc/articles/PMC9777517/ /pubmed/36553394 http://dx.doi.org/10.3390/children9121951 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nagl, Katrin
Bozic, Ina
Berger, Gabriele
Tauschmann, Martin
Blauensteiner, Nicole
Weimann, Katharina
Mader, Julia K.
Rami-Merhar, Birgit
Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title_full Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title_fullStr Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title_full_unstemmed Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title_short Time in Range in Children with Type 1 Diabetes before and during a Diabetes Camp—A Ceiling Effect?
title_sort time in range in children with type 1 diabetes before and during a diabetes camp—a ceiling effect?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777517/
https://www.ncbi.nlm.nih.gov/pubmed/36553394
http://dx.doi.org/10.3390/children9121951
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