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Can Polymorphisms in NLRP3 Inflammasome Complex Be Associated with Postmenopausal Osteoporosis Severity?

The immune system plays a critical role in bone homeostasis and, consequently, in the pathophysiology of postmenopausal osteoporosis (OP) since estrogen deficiency induces the inflammasome and increases production of pro-inflammatory cytokines, such as IL-1β and IL-18. NLRP3 inflammasome complex gen...

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Detalles Bibliográficos
Autores principales: Guaraná, Werbson Lima, Lima, Camilla Albertina Dantas, Barbosa, Alexandre Domingues, Crovella, Sergio, Sandrin-Garcia, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777825/
https://www.ncbi.nlm.nih.gov/pubmed/36553538
http://dx.doi.org/10.3390/genes13122271

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