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Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer
Adolescents and young women (AYA) with breast cancer represent a unique patient population, compared to the general population with breast cancer. We performed a literature review to evaluate the factors that influenced the surgical outcomes in this patient population. Fifty-two studies were identif...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777860/ https://www.ncbi.nlm.nih.gov/pubmed/36554065 http://dx.doi.org/10.3390/healthcare10122542 |
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author | Murphy, Brittany L. Pereslucha, Alicia Boughey, Judy C. |
author_facet | Murphy, Brittany L. Pereslucha, Alicia Boughey, Judy C. |
author_sort | Murphy, Brittany L. |
collection | PubMed |
description | Adolescents and young women (AYA) with breast cancer represent a unique patient population, compared to the general population with breast cancer. We performed a literature review to evaluate the factors that influenced the surgical outcomes in this patient population. Fifty-two studies were identified, which evaluated breast surgery type, axillary surgery, contralateral prophylactic mastectomy (CPM), surgical timing, psychological factors, disparities, and imaging use. AYA patients had equivalent oncologic outcomes with breast conserving surgery (BCS) or mastectomy. CPM did not improve survival. There are limited data on axillary management in the AYA population, and while more data would be beneficial, this is currently extrapolated from the general breast cancer population. A shorter time to initiate treatment correlated to better outcomes, and disparities need to be overcome for optimal outcomes. AYA patients appreciated involvement in clinical decisions, and shared decision making should be considered whenever possible. Providers must keep these factors in mind when counseling AYA patients, regarding the surgical management of breast cancer. |
format | Online Article Text |
id | pubmed-9777860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97778602022-12-23 Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer Murphy, Brittany L. Pereslucha, Alicia Boughey, Judy C. Healthcare (Basel) Review Adolescents and young women (AYA) with breast cancer represent a unique patient population, compared to the general population with breast cancer. We performed a literature review to evaluate the factors that influenced the surgical outcomes in this patient population. Fifty-two studies were identified, which evaluated breast surgery type, axillary surgery, contralateral prophylactic mastectomy (CPM), surgical timing, psychological factors, disparities, and imaging use. AYA patients had equivalent oncologic outcomes with breast conserving surgery (BCS) or mastectomy. CPM did not improve survival. There are limited data on axillary management in the AYA population, and while more data would be beneficial, this is currently extrapolated from the general breast cancer population. A shorter time to initiate treatment correlated to better outcomes, and disparities need to be overcome for optimal outcomes. AYA patients appreciated involvement in clinical decisions, and shared decision making should be considered whenever possible. Providers must keep these factors in mind when counseling AYA patients, regarding the surgical management of breast cancer. MDPI 2022-12-15 /pmc/articles/PMC9777860/ /pubmed/36554065 http://dx.doi.org/10.3390/healthcare10122542 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Murphy, Brittany L. Pereslucha, Alicia Boughey, Judy C. Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title | Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title_full | Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title_fullStr | Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title_full_unstemmed | Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title_short | Current Considerations in Surgical Treatment for Adolescents and Young Women with Breast Cancer |
title_sort | current considerations in surgical treatment for adolescents and young women with breast cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777860/ https://www.ncbi.nlm.nih.gov/pubmed/36554065 http://dx.doi.org/10.3390/healthcare10122542 |
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