Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond

R-loops are DNA–RNA hybrids that play multifunctional roles in gene regulation, including replication, transcription, transcription–replication collision, epigenetics, and preserving the integrity of the genome. The aberrant formation and accumulation of unscheduled R-loops can disrupt gene expressi...

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Detalles Bibliográficos
Autores principales: Khan, Essak S., Danckwardt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777984/
https://www.ncbi.nlm.nih.gov/pubmed/36553448
http://dx.doi.org/10.3390/genes13122181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777984/
https://www.ncbi.nlm.nih.gov/pubmed/36553448
http://dx.doi.org/10.3390/genes13122181

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