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Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond
R-loops are DNA–RNA hybrids that play multifunctional roles in gene regulation, including replication, transcription, transcription–replication collision, epigenetics, and preserving the integrity of the genome. The aberrant formation and accumulation of unscheduled R-loops can disrupt gene expressi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777984/ https://www.ncbi.nlm.nih.gov/pubmed/36553448 http://dx.doi.org/10.3390/genes13122181 |