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CELO Fiber1 Knob Is a Promising Candidate to Modify the Tropism of Adenoviral Vectors

Fowl adenovirus 4 (FAdV-4) has the potential to be constructed as a gene transfer vector for human gene therapy or vaccine development to avoid the pre-existing immunity to human adenoviruses. To enhance the transduction of FAdV-4 to human cells, CELO fiber1 knob (CF1K) was chosen to replace the fib...

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Detalles Bibliográficos
Autores principales:	Sun, Yangyang, Zou, Xiaohui, Guo, Xiaojuan, Yang, Chunlei, Hung, Tao, Lu, Zhuozhuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778213/ https://www.ncbi.nlm.nih.gov/pubmed/36553583 http://dx.doi.org/10.3390/genes13122316

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