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Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778348/ https://www.ncbi.nlm.nih.gov/pubmed/36553945 http://dx.doi.org/10.3390/healthcare10122421 |
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author | Alhlayl, Adel S. Alzghaibi, Haitham A. Jamal, Qazi Mohammad Sajid |
author_facet | Alhlayl, Adel S. Alzghaibi, Haitham A. Jamal, Qazi Mohammad Sajid |
author_sort | Alhlayl, Adel S. |
collection | PubMed |
description | Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is considered the first register of its kind that can link information from patients to clinical data and has been established to answer different information needs about MS. Aim: To elucidate the trends in patterns of medicines currently used by people with MS in the UK MS register. Methods: This study follows an exploratory descriptive design using the UK MS register as data resource. A number of 4516 people completed the EQ-5D survey out of 8736 people who have given their consent to answer online questionnaires which represents around 52% of the register total population. Descriptive analysis and tests were performed with SPSS to address the research objectives. Results: There are several medicine names entered by people with MS in their profiles. These medicines are used either to manage MS symptoms or to treat its associated complications. Among the medicine types revealed in this study, disease modifying drugs (DMDs), muscle relaxants, and anticonvulsants are the medicine types mainly used by people with MS followed by antidepressant and antianxiety medicines. Conclusions: From the antidepressants used most widely, amitriptyline was chosen as a subject medicine for further investigation in the remaining studies of this research due to its high frequency use, the elevated depression rates discovered among people with MS who seek information on it online, and the high online content noted on websites about this medicine. |
format | Online Article Text |
id | pubmed-9778348 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97783482022-12-23 Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study Alhlayl, Adel S. Alzghaibi, Haitham A. Jamal, Qazi Mohammad Sajid Healthcare (Basel) Article Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is considered the first register of its kind that can link information from patients to clinical data and has been established to answer different information needs about MS. Aim: To elucidate the trends in patterns of medicines currently used by people with MS in the UK MS register. Methods: This study follows an exploratory descriptive design using the UK MS register as data resource. A number of 4516 people completed the EQ-5D survey out of 8736 people who have given their consent to answer online questionnaires which represents around 52% of the register total population. Descriptive analysis and tests were performed with SPSS to address the research objectives. Results: There are several medicine names entered by people with MS in their profiles. These medicines are used either to manage MS symptoms or to treat its associated complications. Among the medicine types revealed in this study, disease modifying drugs (DMDs), muscle relaxants, and anticonvulsants are the medicine types mainly used by people with MS followed by antidepressant and antianxiety medicines. Conclusions: From the antidepressants used most widely, amitriptyline was chosen as a subject medicine for further investigation in the remaining studies of this research due to its high frequency use, the elevated depression rates discovered among people with MS who seek information on it online, and the high online content noted on websites about this medicine. MDPI 2022-11-30 /pmc/articles/PMC9778348/ /pubmed/36553945 http://dx.doi.org/10.3390/healthcare10122421 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Alhlayl, Adel S. Alzghaibi, Haitham A. Jamal, Qazi Mohammad Sajid Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title | Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title_full | Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title_fullStr | Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title_full_unstemmed | Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title_short | Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study |
title_sort | determining current medications usage within a cohort of patients in the uk—a descriptive retrospective study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778348/ https://www.ncbi.nlm.nih.gov/pubmed/36553945 http://dx.doi.org/10.3390/healthcare10122421 |
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