Cargando…

Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study

Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is c...

Descripción completa

Detalles Bibliográficos
Autores principales: Alhlayl, Adel S., Alzghaibi, Haitham A., Jamal, Qazi Mohammad Sajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778348/
https://www.ncbi.nlm.nih.gov/pubmed/36553945
http://dx.doi.org/10.3390/healthcare10122421
_version_ 1784856336504193024
author Alhlayl, Adel S.
Alzghaibi, Haitham A.
Jamal, Qazi Mohammad Sajid
author_facet Alhlayl, Adel S.
Alzghaibi, Haitham A.
Jamal, Qazi Mohammad Sajid
author_sort Alhlayl, Adel S.
collection PubMed
description Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is considered the first register of its kind that can link information from patients to clinical data and has been established to answer different information needs about MS. Aim: To elucidate the trends in patterns of medicines currently used by people with MS in the UK MS register. Methods: This study follows an exploratory descriptive design using the UK MS register as data resource. A number of 4516 people completed the EQ-5D survey out of 8736 people who have given their consent to answer online questionnaires which represents around 52% of the register total population. Descriptive analysis and tests were performed with SPSS to address the research objectives. Results: There are several medicine names entered by people with MS in their profiles. These medicines are used either to manage MS symptoms or to treat its associated complications. Among the medicine types revealed in this study, disease modifying drugs (DMDs), muscle relaxants, and anticonvulsants are the medicine types mainly used by people with MS followed by antidepressant and antianxiety medicines. Conclusions: From the antidepressants used most widely, amitriptyline was chosen as a subject medicine for further investigation in the remaining studies of this research due to its high frequency use, the elevated depression rates discovered among people with MS who seek information on it online, and the high online content noted on websites about this medicine.
format Online
Article
Text
id pubmed-9778348
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97783482022-12-23 Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study Alhlayl, Adel S. Alzghaibi, Haitham A. Jamal, Qazi Mohammad Sajid Healthcare (Basel) Article Swansea University’s United Kingdom (UK) Multiple Sclerosis (MS) Register is a platform that contains information on more than 17,600 people with MS living in the UK. The register has been in operation since 2011 and represents comprehensive information about people living with MS in the UK. It is considered the first register of its kind that can link information from patients to clinical data and has been established to answer different information needs about MS. Aim: To elucidate the trends in patterns of medicines currently used by people with MS in the UK MS register. Methods: This study follows an exploratory descriptive design using the UK MS register as data resource. A number of 4516 people completed the EQ-5D survey out of 8736 people who have given their consent to answer online questionnaires which represents around 52% of the register total population. Descriptive analysis and tests were performed with SPSS to address the research objectives. Results: There are several medicine names entered by people with MS in their profiles. These medicines are used either to manage MS symptoms or to treat its associated complications. Among the medicine types revealed in this study, disease modifying drugs (DMDs), muscle relaxants, and anticonvulsants are the medicine types mainly used by people with MS followed by antidepressant and antianxiety medicines. Conclusions: From the antidepressants used most widely, amitriptyline was chosen as a subject medicine for further investigation in the remaining studies of this research due to its high frequency use, the elevated depression rates discovered among people with MS who seek information on it online, and the high online content noted on websites about this medicine. MDPI 2022-11-30 /pmc/articles/PMC9778348/ /pubmed/36553945 http://dx.doi.org/10.3390/healthcare10122421 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alhlayl, Adel S.
Alzghaibi, Haitham A.
Jamal, Qazi Mohammad Sajid
Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title_full Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title_fullStr Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title_full_unstemmed Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title_short Determining Current Medications Usage within a Cohort of Patients in the UK—A Descriptive Retrospective Study
title_sort determining current medications usage within a cohort of patients in the uk—a descriptive retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778348/
https://www.ncbi.nlm.nih.gov/pubmed/36553945
http://dx.doi.org/10.3390/healthcare10122421
work_keys_str_mv AT alhlayladels determiningcurrentmedicationsusagewithinacohortofpatientsintheukadescriptiveretrospectivestudy
AT alzghaibihaithama determiningcurrentmedicationsusagewithinacohortofpatientsintheukadescriptiveretrospectivestudy
AT jamalqazimohammadsajid determiningcurrentmedicationsusagewithinacohortofpatientsintheukadescriptiveretrospectivestudy