Cargando…

Administration of oral dosage forms of medicines to children in a resource limited setting

BACKGROUND: There are many paediatric specific challenges such as lack of age-appropriate dosage forms, inability of young children to swallow tablets and capsules and poor acceptability, during administration of oral dosage forms of medications to children. Parents adopt various methods which they...

Descripción completa

Detalles Bibliográficos
Autores principales: Nadeshkumar, Abarna, Sathiadas, Gitanjali, Sri Ranganathan, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778530/
https://www.ncbi.nlm.nih.gov/pubmed/36548310
http://dx.doi.org/10.1371/journal.pone.0276379
_version_ 1784856385086816256
author Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
author_facet Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
author_sort Nadeshkumar, Abarna
collection PubMed
description BACKGROUND: There are many paediatric specific challenges such as lack of age-appropriate dosage forms, inability of young children to swallow tablets and capsules and poor acceptability, during administration of oral dosage forms of medications to children. Parents adopt various methods which they consider best to circumvent this problem. The objective of this study was to describe the administration practice by parents when giving oral dosage forms of medications to children. METHODS: A descriptive cross-sectional study was conducted to assess the administration practice of 1800 oral dosage forms of medications administered to children under the age of 12 years using validated indicators. A pre-tested interviewer-administered questionnaire given to parents or caregivers was used to collect the necessary data. The data were analysed using descriptive statistics. RESULTS: Data from 1800 oral dosage forms was obtained from 663 children. Of the 1287 solid dosage forms, almost one-third were manipulated by parents at the time of giving the medications to children. They were crushed and dissolved in water given to children. In about 17% of instances safety of water was questionable. In 92% of instances, measuring device was found to be inappropriate. CONCLUSION: Administration of oral dosage forms of medications to children is far from ideal and hinders successful use of medications in children.
format Online
Article
Text
id pubmed-9778530
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-97785302022-12-23 Administration of oral dosage forms of medicines to children in a resource limited setting Nadeshkumar, Abarna Sathiadas, Gitanjali Sri Ranganathan, Shalini PLoS One Research Article BACKGROUND: There are many paediatric specific challenges such as lack of age-appropriate dosage forms, inability of young children to swallow tablets and capsules and poor acceptability, during administration of oral dosage forms of medications to children. Parents adopt various methods which they consider best to circumvent this problem. The objective of this study was to describe the administration practice by parents when giving oral dosage forms of medications to children. METHODS: A descriptive cross-sectional study was conducted to assess the administration practice of 1800 oral dosage forms of medications administered to children under the age of 12 years using validated indicators. A pre-tested interviewer-administered questionnaire given to parents or caregivers was used to collect the necessary data. The data were analysed using descriptive statistics. RESULTS: Data from 1800 oral dosage forms was obtained from 663 children. Of the 1287 solid dosage forms, almost one-third were manipulated by parents at the time of giving the medications to children. They were crushed and dissolved in water given to children. In about 17% of instances safety of water was questionable. In 92% of instances, measuring device was found to be inappropriate. CONCLUSION: Administration of oral dosage forms of medications to children is far from ideal and hinders successful use of medications in children. Public Library of Science 2022-12-22 /pmc/articles/PMC9778530/ /pubmed/36548310 http://dx.doi.org/10.1371/journal.pone.0276379 Text en © 2022 Nadeshkumar et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
Administration of oral dosage forms of medicines to children in a resource limited setting
title Administration of oral dosage forms of medicines to children in a resource limited setting
title_full Administration of oral dosage forms of medicines to children in a resource limited setting
title_fullStr Administration of oral dosage forms of medicines to children in a resource limited setting
title_full_unstemmed Administration of oral dosage forms of medicines to children in a resource limited setting
title_short Administration of oral dosage forms of medicines to children in a resource limited setting
title_sort administration of oral dosage forms of medicines to children in a resource limited setting
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778530/
https://www.ncbi.nlm.nih.gov/pubmed/36548310
http://dx.doi.org/10.1371/journal.pone.0276379
work_keys_str_mv AT nadeshkumarabarna administrationoforaldosageformsofmedicinestochildreninaresourcelimitedsetting
AT sathiadasgitanjali administrationoforaldosageformsofmedicinestochildreninaresourcelimitedsetting
AT sriranganathanshalini administrationoforaldosageformsofmedicinestochildreninaresourcelimitedsetting