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The Combination of Panobinostat and Melphalan for the Treatment of Patients with Multiple Myeloma
Histone deacetylase inhibitors show synergy with several genotoxic drugs. Herein, we investigated the biological impact of the combined treatment of panobinostat and melphalan in multiple myeloma (MM). DNA damage response (DDR) parameters and the expression of DDR-associated genes were analyzed in b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778728/ https://www.ncbi.nlm.nih.gov/pubmed/36555311 http://dx.doi.org/10.3390/ijms232415671 |