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The Combination of Panobinostat and Melphalan for the Treatment of Patients with Multiple Myeloma

Histone deacetylase inhibitors show synergy with several genotoxic drugs. Herein, we investigated the biological impact of the combined treatment of panobinostat and melphalan in multiple myeloma (MM). DNA damage response (DDR) parameters and the expression of DDR-associated genes were analyzed in b...

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Detalles Bibliográficos
Autores principales: Gkotzamanidou, Maria, Terpos, Evangelos, Dimopoulos, Meletios A., Souliotis, Vassilis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778728/
https://www.ncbi.nlm.nih.gov/pubmed/36555311
http://dx.doi.org/10.3390/ijms232415671