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Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak

The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of...

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Autores principales: Guerrero-Vadillo, María, Peñuelas, Marina, Domínguez, Ángela, Godoy, Pere, Gómez-Barroso, Diana, Soldevila, Nuria, Izquierdo, Conchita, Martínez, Ana, Torner, Nuria, Avellón, Ana, Rius, Cristina, Varela, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778781/
https://www.ncbi.nlm.nih.gov/pubmed/36554666
http://dx.doi.org/10.3390/ijerph192416775
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author Guerrero-Vadillo, María
Peñuelas, Marina
Domínguez, Ángela
Godoy, Pere
Gómez-Barroso, Diana
Soldevila, Nuria
Izquierdo, Conchita
Martínez, Ana
Torner, Nuria
Avellón, Ana
Rius, Cristina
Varela, Carmen
author_facet Guerrero-Vadillo, María
Peñuelas, Marina
Domínguez, Ángela
Godoy, Pere
Gómez-Barroso, Diana
Soldevila, Nuria
Izquierdo, Conchita
Martínez, Ana
Torner, Nuria
Avellón, Ana
Rius, Cristina
Varela, Carmen
author_sort Guerrero-Vadillo, María
collection PubMed
description The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016–2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space–time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15–44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space–time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging.
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spelling pubmed-97787812022-12-23 Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak Guerrero-Vadillo, María Peñuelas, Marina Domínguez, Ángela Godoy, Pere Gómez-Barroso, Diana Soldevila, Nuria Izquierdo, Conchita Martínez, Ana Torner, Nuria Avellón, Ana Rius, Cristina Varela, Carmen Int J Environ Res Public Health Article The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016–2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space–time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15–44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space–time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging. MDPI 2022-12-14 /pmc/articles/PMC9778781/ /pubmed/36554666 http://dx.doi.org/10.3390/ijerph192416775 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Guerrero-Vadillo, María
Peñuelas, Marina
Domínguez, Ángela
Godoy, Pere
Gómez-Barroso, Diana
Soldevila, Nuria
Izquierdo, Conchita
Martínez, Ana
Torner, Nuria
Avellón, Ana
Rius, Cristina
Varela, Carmen
Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_full Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_fullStr Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_full_unstemmed Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_short Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_sort epidemiological characteristics and spatio-temporal distribution of hepatitis a in spain in the context of the 2016/2017 european outbreak
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778781/
https://www.ncbi.nlm.nih.gov/pubmed/36554666
http://dx.doi.org/10.3390/ijerph192416775
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