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Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778781/ https://www.ncbi.nlm.nih.gov/pubmed/36554666 http://dx.doi.org/10.3390/ijerph192416775 |
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author | Guerrero-Vadillo, María Peñuelas, Marina Domínguez, Ángela Godoy, Pere Gómez-Barroso, Diana Soldevila, Nuria Izquierdo, Conchita Martínez, Ana Torner, Nuria Avellón, Ana Rius, Cristina Varela, Carmen |
author_facet | Guerrero-Vadillo, María Peñuelas, Marina Domínguez, Ángela Godoy, Pere Gómez-Barroso, Diana Soldevila, Nuria Izquierdo, Conchita Martínez, Ana Torner, Nuria Avellón, Ana Rius, Cristina Varela, Carmen |
author_sort | Guerrero-Vadillo, María |
collection | PubMed |
description | The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016–2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space–time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15–44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space–time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging. |
format | Online Article Text |
id | pubmed-9778781 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97787812022-12-23 Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak Guerrero-Vadillo, María Peñuelas, Marina Domínguez, Ángela Godoy, Pere Gómez-Barroso, Diana Soldevila, Nuria Izquierdo, Conchita Martínez, Ana Torner, Nuria Avellón, Ana Rius, Cristina Varela, Carmen Int J Environ Res Public Health Article The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016–2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space–time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15–44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space–time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging. MDPI 2022-12-14 /pmc/articles/PMC9778781/ /pubmed/36554666 http://dx.doi.org/10.3390/ijerph192416775 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Guerrero-Vadillo, María Peñuelas, Marina Domínguez, Ángela Godoy, Pere Gómez-Barroso, Diana Soldevila, Nuria Izquierdo, Conchita Martínez, Ana Torner, Nuria Avellón, Ana Rius, Cristina Varela, Carmen Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title | Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title_full | Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title_fullStr | Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title_full_unstemmed | Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title_short | Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak |
title_sort | epidemiological characteristics and spatio-temporal distribution of hepatitis a in spain in the context of the 2016/2017 european outbreak |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778781/ https://www.ncbi.nlm.nih.gov/pubmed/36554666 http://dx.doi.org/10.3390/ijerph192416775 |
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