Pancreatic Secretory Trypsin Inhibitor (SPINK1) Gene Mutation in Patients with Acute Alcohol Pancreatitis (AAP) Compared to Healthy Controls and Heavy Alcohol Users without Pancreatitis

Only 3–5% of heavy alcohol users develop acute alcohol pancreatitis (AAP). This suggests that additional triggers are required to initiate the inflammatory process. Genetic susceptibility contributes to the development of AAP, and SPINK1 mutation is a documented risk factor. We investigated the prev...

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Detalles Bibliográficos
Autores principales: Nikkola, Anssi, Mäkelä, Kari Antero, Herzig, Karl-Heinz, Mutt, Shivaprakash Jagalur, Prasannan, Aishwarya, Seppänen, Hanna, Lehtimäki, Terho, Kähönen, Mika, Raitakari, Olli, Seppälä, Ilkka, Pakkanen, Pihla, Nordback, Isto, Sand, Juhani, Laukkarinen, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778821/
https://www.ncbi.nlm.nih.gov/pubmed/36555366
http://dx.doi.org/10.3390/ijms232415726

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