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High Dose Pharmaceutical Grade Biotin (MD1003) Accelerates Differentiation of Murine and Grafted Human Oligodendrocyte Progenitor Cells In Vivo

Accumulating evidences suggest a strong correlation between metabolic changes and neurodegeneration in CNS demyelinating diseases such as multiple sclerosis (MS). Biotin, an essential cofactor for five carboxylases, is expressed by oligodendrocytes and involved in fatty acid synthesis and energy pro...

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Detalles Bibliográficos
Autores principales: Levy, Marion J. F., Garcia-Diaz, Beatriz, Sedel, Frédéric, Baron-Van Evercooren, Anne, Mozafari, Sabah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778913/
https://www.ncbi.nlm.nih.gov/pubmed/36555377
http://dx.doi.org/10.3390/ijms232415733