Cargando…

Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice

CRISPR-Cas9-mediated leptin (Lep) knockout (KO) mice exhibited prominent phenotypes for constipation, even though they were not compared with other model animals. This study compared the stool excretion, gastrointestinal motility, histological structure, mucin secretion, and enteric nerve function i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji Eun, Seol, Ayun, Choi, Yun Ju, Lee, Su Jin, Jin, You Jeong, Roh, Yu Jeong, Song, Hee Jin, Hong, Jin Tae, Hwang, Dae Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778951/ https://www.ncbi.nlm.nih.gov/pubmed/36548335 http://dx.doi.org/10.1371/journal.pone.0276445

Ejemplares similares

Dysregulation of the Enteric Nervous System in the Mid Colon of Complement Component 3 Knockout Mice with Constipation Phenotypes
por: Choi, Yun Ju, et al.
Publicado: (2022)

Dipterocarpus tuberculatus as a promising anti-obesity treatment in Lep knockout mice
por: Roh, Yu Jeong, et al.
Publicado: (2023)

Comparison of immunophenotypes between Rag2 knockout mice derived from two different sources
por: Roh, Yu Jeong, et al.
Publicado: (2023)

Complement C3-Deficiency-Induced Constipation in FVB/N-C3(em1Hlee)/Korl Knockout Mice Was Significantly Relieved by Uridine and Liriope platyphylla L. Extracts
por: Song, Hee-Jin, et al.
Publicado: (2023)

Molecular Characterization of Constipation Disease as Novel Phenotypes in CRISPR-Cas9-Generated Leptin Knockout Mice with Obesity
por: Kim, Ji Eun, et al.
Publicado: (2020)

Dysbiosis of Fecal Microbiota From Complement 3 Knockout Mice With Constipation Phenotypes Contributes to Development of Defecation Delay
por: Choi, Yun Ju, et al.
Publicado: (2021)

Dysbiosis of Fecal Microbiota in Tg2576 Mice for Alzheimer’s Disease during Pathological Constipation
por: Kim, Ji-Eun, et al.
Publicado: (2022)

Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide-induced constipation of SD rats
por: Kim, Ji Eun, et al.
Publicado: (2023)

Characterisation of changes in global genes expression in the lung of ICR mice in response to the inflammation and fibrosis induced by polystyrene nanoplastics inhalation
por: Jin, You Jeong, et al.
Publicado: (2023)

Anti-Atopic Dermatitis Effects of Abietic Acid Isolated from Rosin under Condition Optimized by Response Surface Methodology in DNCB-Spread BALB/c Mice
por: Park, Jumin, et al.
Publicado: (2023)

Promotion of the inflammatory response in mid colon of complement component 3 knockout mice
por: Choi, Yun Ju, et al.
Publicado: (2022)

Protective Effects of Dipterocarpus tuberculatus in Blue Light-Induced Macular Degeneration in A2E-Laden ARPE19 Cells and Retina of Balb/c Mice
por: Lee, Su Jin, et al.
Publicado: (2023)

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics
por: Choi, Yun Ju, et al.
Publicado: (2021)

Compositional changes in fecal microbiota in a new Parkinson's disease model: C57BL/6-Tg(NSE-haSyn) mice
por: Kim, Ji Eun, et al.
Publicado: (2023)

Therapeutic Effects of Aloe saponaria against Ulcerative Colitis Induced by Dextran Sulfate Sodium
por: Kweon, Do Yeong, et al.
Publicado: (2023)

Chemosensitivity to doxorubicin in primary cells derived from tumor of FVB/N-Trp53(tm1Hw1) with TALEN-mediated Trp53 mutant gene
por: Yun, Woobin, et al.
Publicado: (2023)

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Effect of Obesity and High-Density Lipoprotein Concentration on the Pathological Characteristics of Alzheimer’s Disease in High-Fat Diet-Fed Mice
por: Choi, Moonseok, et al.
Publicado: (2022)

Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
por: Jin, Heung Yong, et al.
Publicado: (2013)

Adiposity Reduction by Cucumis melo var. gaettongchamoe Extract in High-Fat Diet-Induced Obese Mice
por: Park, Sun Young, et al.
Publicado: (2023)

Effects of lobeglitazone on insulin resistance and hepatic steatosis in high-fat diet-fed mice
por: Choi, Bong-Hoi, et al.
Publicado: (2018)

Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice
por: Powell, David R., et al.
Publicado: (2015)

Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model
por: Kim, Ji Eun, et al.
Publicado: (2019)

Anti-obesity and fatty liver-preventing activities of Lonicera caerulea in high-fat diet-fed mice
por: Kim, Joo Wan, et al.
Publicado: (2018)

Effects of exercise on high-fat diet–induced non-alcoholic fatty liver disease and lipid metabolism in ApoE knockout mice
por: Huang, Wen-Ching, et al.
Publicado: (2022)

The Eyelid Meibomian Gland Deficiency in Fucosyltransferase 1 Knockout Mice
por: Yoon, Chang Ho, et al.
Publicado: (2022)

Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response
por: Kim, Ji Eun, et al.
Publicado: (2019)

Forsythia Fruit Prevents Fulminant Hepatitis in Mice and Ameliorates Inflammation in Murine Macrophages
por: Jeong, Yun Hee, et al.
Publicado: (2021)

Characterization the response of Korl:ICR mice to loperamide induced constipation
por: Kim, Ji Eun, et al.
Publicado: (2016)

Pentacyclic triterpenoid-rich fraction of the Hardy kiwi (Actinidia arguta) improves brain dysfunction in high fat diet-induced obese mice
por: Ha, Jeong Su, et al.
Publicado: (2020)

Citrus junos Tanaka Peel Extract Exerts Antidiabetic Effects via AMPK and PPAR-γ both In Vitro and In Vivo in Mice Fed a High-Fat Diet
por: Kim, Sung Hee, et al.
Publicado: (2013)

Inflammatory response in the mid colon of ICR mice treated with polystyrene microplastics for two weeks
por: Choi, Yun Ju, et al.
Publicado: (2021)

Effects of High-Fat Diet on Stress Response in Male and Female Wildtype and Prolactin Knockout Mice
por: Kalyani, Manu, et al.
Publicado: (2016)

Improvement of Adipose Macrophage Polarization in High Fat Diet-Induced Obese GHSR Knockout Mice
por: Yuan, Fang, et al.
Publicado: (2018)

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice
por: Dijkstra, M. H., et al.
Publicado: (2014)

Effects of treadmill exercise on skeletal muscle mTOR signaling pathway in high-fat diet-induced obese mice
por: Woo, Jin Hee, et al.
Publicado: (2016)

Lipocalin-2 Deficiency Reduces Hepatic and Hippocampal Triggering Receptor Expressed on Myeloid Cells-2 Expressions in High-Fat Diet/Streptozotocin-Induced Diabetic Mice
por: Shin, Hyun Joo, et al.
Publicado: (2022)

Comparative study of the effects of diosmin and diosmetin on fat accumulation, dyslipidemia, and glucose intolerance in mice fed a high‐fat high‐sucrose diet
por: Chung, Sangwon, et al.
Publicado: (2020)

Dehydrozingerone inhibits renal lipotoxicity in high‐fat diet–induced obese mice
por: Lee, Eun Soo, et al.
Publicado: (2021)

TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice
por: Lee, Jong Youl, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gk40sen025vcfck36dcakjiho2