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Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice

CRISPR-Cas9-mediated leptin (Lep) knockout (KO) mice exhibited prominent phenotypes for constipation, even though they were not compared with other model animals. This study compared the stool excretion, gastrointestinal motility, histological structure, mucin secretion, and enteric nerve function i...

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Detalles Bibliográficos
Autores principales:	Kim, Ji Eun, Seol, Ayun, Choi, Yun Ju, Lee, Su Jin, Jin, You Jeong, Roh, Yu Jeong, Song, Hee Jin, Hong, Jin Tae, Hwang, Dae Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778951/ https://www.ncbi.nlm.nih.gov/pubmed/36548335 http://dx.doi.org/10.1371/journal.pone.0276445

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