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Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries
Catheter-induced dissections (CID) of coronary arteries and/or the aorta are among the most dangerous complications of percutaneous coronary procedures, yet the data on their risk factors are anecdotal. Logistic regression and five more advanced machine learning techniques were applied to determine...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779019/ https://www.ncbi.nlm.nih.gov/pubmed/36554883 http://dx.doi.org/10.3390/ijerph192417002 |
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author | Klaudel, Jacek Klaudel, Barbara Glaza, Michał Trenkner, Wojciech Derejko, Paweł Szołkiewicz, Marek |
author_facet | Klaudel, Jacek Klaudel, Barbara Glaza, Michał Trenkner, Wojciech Derejko, Paweł Szołkiewicz, Marek |
author_sort | Klaudel, Jacek |
collection | PubMed |
description | Catheter-induced dissections (CID) of coronary arteries and/or the aorta are among the most dangerous complications of percutaneous coronary procedures, yet the data on their risk factors are anecdotal. Logistic regression and five more advanced machine learning techniques were applied to determine the most significant predictors of dissection. Model performance comparison and feature importance ranking were evaluated. We identified 124 cases of CID in electronic databases containing 84,223 records of diagnostic and interventional coronary procedures from the years 2000–2022. Based on the f1-score, Extreme Gradient Boosting (XGBoost) was found to have the optimal balance between positive predictive value (precision) and sensitivity (recall). As by the XGBoost, the strongest predictors were the use of a guiding catheter (angioplasty), small/stenotic ostium, radial access, hypertension, acute myocardial infarction, prior angioplasty, female gender, chronic renal failure, atypical coronary origin, and chronic obstructive pulmonary disease. Risk prediction can be bolstered with machine learning algorithms and provide valuable clinical decision support. Based on the proposed model, a profile of ‘a perfect dissection candidate’ can be defined. In patients with ‘a clustering’ of dissection predictors, a less aggressive catheter and/or modification of the access site should be considered. |
format | Online Article Text |
id | pubmed-9779019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97790192022-12-23 Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries Klaudel, Jacek Klaudel, Barbara Glaza, Michał Trenkner, Wojciech Derejko, Paweł Szołkiewicz, Marek Int J Environ Res Public Health Article Catheter-induced dissections (CID) of coronary arteries and/or the aorta are among the most dangerous complications of percutaneous coronary procedures, yet the data on their risk factors are anecdotal. Logistic regression and five more advanced machine learning techniques were applied to determine the most significant predictors of dissection. Model performance comparison and feature importance ranking were evaluated. We identified 124 cases of CID in electronic databases containing 84,223 records of diagnostic and interventional coronary procedures from the years 2000–2022. Based on the f1-score, Extreme Gradient Boosting (XGBoost) was found to have the optimal balance between positive predictive value (precision) and sensitivity (recall). As by the XGBoost, the strongest predictors were the use of a guiding catheter (angioplasty), small/stenotic ostium, radial access, hypertension, acute myocardial infarction, prior angioplasty, female gender, chronic renal failure, atypical coronary origin, and chronic obstructive pulmonary disease. Risk prediction can be bolstered with machine learning algorithms and provide valuable clinical decision support. Based on the proposed model, a profile of ‘a perfect dissection candidate’ can be defined. In patients with ‘a clustering’ of dissection predictors, a less aggressive catheter and/or modification of the access site should be considered. MDPI 2022-12-18 /pmc/articles/PMC9779019/ /pubmed/36554883 http://dx.doi.org/10.3390/ijerph192417002 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Klaudel, Jacek Klaudel, Barbara Glaza, Michał Trenkner, Wojciech Derejko, Paweł Szołkiewicz, Marek Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title | Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title_full | Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title_fullStr | Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title_full_unstemmed | Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title_short | Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries |
title_sort | forewarned is forearmed: machine learning algorithms for the prediction of catheter-induced coronary and aortic injuries |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779019/ https://www.ncbi.nlm.nih.gov/pubmed/36554883 http://dx.doi.org/10.3390/ijerph192417002 |
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