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Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases

The mammalian 14-3-3 family comprises seven intrinsically unstructured, evolutionarily conserved proteins that bind >200 protein targets, thereby modulating cell-signaling pathways. The presence of 14-3-3 proteins in cerebrospinal fluid provides a sensitive and specific biomarker of neuronal dama...

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Detalles Bibliográficos
Autores principales:	Ganne, Akshatha, Balasubramaniam, Meenakshisundaram, Mainali, Nirjal, Atluri, Paavan, Shmookler Reis, Robert J., Ayyadevara, Srinivas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779020/ https://www.ncbi.nlm.nih.gov/pubmed/36555098 http://dx.doi.org/10.3390/ijms232415457

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