Inhibition of JAK1,2 Prevents Fibrotic Remodeling of Pulmonary Vascular Bed and Improves Outcomes in the Rat Model of Chronic Thromboembolic Pulmonary Hypertension

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute pulmonary embolism with poor clinical outcomes. Therapeutic approaches to prevention of fibrotic remodeling of the pulmonary vascular bed in CTEPH are limited. In this work, we tested the hypothesis that Janus kina...

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Detalles Bibliográficos
Autores principales: Karpov, Andrei A., Mihailova, Aleksandra M., Shilenko, Leonid A., Vaulina, Dariya D., Sidorova, Elizaveta E., Akhmetova, Anna A., Docshin, Pavel M., Krasichkov, Alexander S., Sanarova, Kseniia E., Moiseeva, Olga M., Galagudza, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779027/
https://www.ncbi.nlm.nih.gov/pubmed/36555286
http://dx.doi.org/10.3390/ijms232415646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779027/
https://www.ncbi.nlm.nih.gov/pubmed/36555286
http://dx.doi.org/10.3390/ijms232415646

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