Intestinal Stem Cells Damaged by Deoxycholic Acid via AHR Pathway Contributes to Mucosal Barrier Dysfunction in High-Fat Feeding Mice

High-fat exposure leads to impaired intestinal barrier function by disrupting the function of intestinal stem cells (ISCs); however, the exact mechanism of this phenomenon is still not known. We hypothesize that high concentrations of deoxycholic acid (DCA) in response to a high-fat diet (HFD) affec...

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Detalles Bibliográficos
Autores principales: Liu, Leheng, Xu, Jingxian, Xu, Xianjun, Mao, Tiancheng, Niu, Wenlu, Wu, Xiaowan, Lu, Lungen, Zhou, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779098/
https://www.ncbi.nlm.nih.gov/pubmed/36555220
http://dx.doi.org/10.3390/ijms232415578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779098/
https://www.ncbi.nlm.nih.gov/pubmed/36555220
http://dx.doi.org/10.3390/ijms232415578

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