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Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia

In this prospective longitudinal cohort study, we explored the characteristics of older people with lower respiratory muscle strength, according to sarcopenia severity, over the course of 1 year. The maximum expiratory pressure (MEP), grip strength, walking speed, and skeletal muscle mass index of 5...

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Autores principales: Sawaya, Yohei, Hirose, Tamaki, Ishizaka, Masahiro, Shiba, Takahiro, Sato, Ryo, Kubo, Akira, Urano, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779222/
https://www.ncbi.nlm.nih.gov/pubmed/36554450
http://dx.doi.org/10.3390/ijerph192416571
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author Sawaya, Yohei
Hirose, Tamaki
Ishizaka, Masahiro
Shiba, Takahiro
Sato, Ryo
Kubo, Akira
Urano, Tomohiko
author_facet Sawaya, Yohei
Hirose, Tamaki
Ishizaka, Masahiro
Shiba, Takahiro
Sato, Ryo
Kubo, Akira
Urano, Tomohiko
author_sort Sawaya, Yohei
collection PubMed
description In this prospective longitudinal cohort study, we explored the characteristics of older people with lower respiratory muscle strength, according to sarcopenia severity, over the course of 1 year. The maximum expiratory pressure (MEP), grip strength, walking speed, and skeletal muscle mass index of 58 participants (28 men, 30 women; mean age, 76.9 ± 7.7 years) were measured at baseline and at the 1-year follow-up. Participants were classified into a decreased MEP group (n = 29; MEP decreased by ≥10% after 1 year) and a non-decreased MEP group (n = 29; MEP decreased by <10%). Sarcopenia status in the mild direction at baseline was significantly associated with MEP decline after one year. Repeated two-way analysis of variance showed significant main effects of measurement time (p < 0.001) and severity of sarcopenia (p = 0.026), as well as a significant interaction effect (p = 0.006). Surprisingly, MEP decreased significantly in the non-sarcopenia and sarcopenia groups, but not in the severe sarcopenia group. Thus, individuals without sarcopenia and those with moderate sarcopenia at baseline are predisposed to MEP decline and should be closely monitored for signs of such decline and associated adverse events.
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spelling pubmed-97792222022-12-23 Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia Sawaya, Yohei Hirose, Tamaki Ishizaka, Masahiro Shiba, Takahiro Sato, Ryo Kubo, Akira Urano, Tomohiko Int J Environ Res Public Health Article In this prospective longitudinal cohort study, we explored the characteristics of older people with lower respiratory muscle strength, according to sarcopenia severity, over the course of 1 year. The maximum expiratory pressure (MEP), grip strength, walking speed, and skeletal muscle mass index of 58 participants (28 men, 30 women; mean age, 76.9 ± 7.7 years) were measured at baseline and at the 1-year follow-up. Participants were classified into a decreased MEP group (n = 29; MEP decreased by ≥10% after 1 year) and a non-decreased MEP group (n = 29; MEP decreased by <10%). Sarcopenia status in the mild direction at baseline was significantly associated with MEP decline after one year. Repeated two-way analysis of variance showed significant main effects of measurement time (p < 0.001) and severity of sarcopenia (p = 0.026), as well as a significant interaction effect (p = 0.006). Surprisingly, MEP decreased significantly in the non-sarcopenia and sarcopenia groups, but not in the severe sarcopenia group. Thus, individuals without sarcopenia and those with moderate sarcopenia at baseline are predisposed to MEP decline and should be closely monitored for signs of such decline and associated adverse events. MDPI 2022-12-09 /pmc/articles/PMC9779222/ /pubmed/36554450 http://dx.doi.org/10.3390/ijerph192416571 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sawaya, Yohei
Hirose, Tamaki
Ishizaka, Masahiro
Shiba, Takahiro
Sato, Ryo
Kubo, Akira
Urano, Tomohiko
Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title_full Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title_fullStr Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title_full_unstemmed Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title_short Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
title_sort patterns of changes in respiratory muscle strength over 1 year in non-sarcopenia, sarcopenia, and severe sarcopenia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779222/
https://www.ncbi.nlm.nih.gov/pubmed/36554450
http://dx.doi.org/10.3390/ijerph192416571
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