The Essential Role of Prolines and Their Conformation in Allosteric Regulation of Kaiso Zinc Finger DNA-Binding Activity by the Adjacent C-Terminal Loop

Kaiso is a methyl-DNA-binding protein containing three C2H2 zinc fingers with a C-terminal extension that participates in DNA binding. The linker between the last zinc finger and the DNA-binding portion of the extension contains two prolines that are highly conserved in vertebrates and in cognate ZB...

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Detalles Bibliográficos
Autores principales: Belova, Elena, Maksimenko, Oksana, Georgiev, Pavel, Bonchuk, Artem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779254/
https://www.ncbi.nlm.nih.gov/pubmed/36555132
http://dx.doi.org/10.3390/ijms232415494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779254/
https://www.ncbi.nlm.nih.gov/pubmed/36555132
http://dx.doi.org/10.3390/ijms232415494

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