The Chromatin Structure at the MECP2 Gene and In Silico Prediction of Potential Coding and Non-Coding MECP2 Splice Variants

Methyl CpG binding protein 2 (MeCP2) is an epigenetic reader that binds to methylated CpG dinucleotides and regulates gene transcription. Mecp2/MECP2 gene has 4 exons, encoding for protein isoforms MeCP2E1 and MeCP2E2. MeCP2 plays key roles in neurodevelopment, therefore, its gain- and loss-of-funct...

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Detalles Bibliográficos
Autores principales: Shevkoplyas, Danilo, Vuu, Yen My, Davie, James R., Rastegar, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779294/
https://www.ncbi.nlm.nih.gov/pubmed/36555295
http://dx.doi.org/10.3390/ijms232415643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779294/
https://www.ncbi.nlm.nih.gov/pubmed/36555295
http://dx.doi.org/10.3390/ijms232415643

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