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Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective

(1) Background: Multimorbidity has become one of the key issues in the public health sector. This study aims to explore the patterns and health-ecological factors of multimorbidity in China to propose policy recommendations for the management of chronic diseases in the elderly. (2) Methods: A multi-...

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Autores principales: Chen, Yiming, Shi, Lei, Zheng, Xiao, Yang, Juan, Xue, Yaqing, Xiao, Shujuan, Xue, Benli, Zhang, Jiachi, Li, Xinru, Lin, Huang, Ma, Chao, Zhang, Chichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779369/
https://www.ncbi.nlm.nih.gov/pubmed/36554647
http://dx.doi.org/10.3390/ijerph192416756
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author Chen, Yiming
Shi, Lei
Zheng, Xiao
Yang, Juan
Xue, Yaqing
Xiao, Shujuan
Xue, Benli
Zhang, Jiachi
Li, Xinru
Lin, Huang
Ma, Chao
Zhang, Chichen
author_facet Chen, Yiming
Shi, Lei
Zheng, Xiao
Yang, Juan
Xue, Yaqing
Xiao, Shujuan
Xue, Benli
Zhang, Jiachi
Li, Xinru
Lin, Huang
Ma, Chao
Zhang, Chichen
author_sort Chen, Yiming
collection PubMed
description (1) Background: Multimorbidity has become one of the key issues in the public health sector. This study aims to explore the patterns and health-ecological factors of multimorbidity in China to propose policy recommendations for the management of chronic diseases in the elderly. (2) Methods: A multi-stage random sampling method was used to conduct a questionnaire survey on 3637 older adults aged 60 and older in Shanxi, China. Association rule mining analysis (ARM) and network analysis were applied to analyze the patterns of multimorbidity. The health-ecological model was adopted to explore the potential associated factors of multimorbidity in a multidimensional perspective. A hierarchical multiple logistic model was employed to investigate the association strengths reflected by adjusted odds ratios and 95% confidence. (3) Results: Multimorbidity occurred in 20.95% of the respondents. The graph of network analysis showed that there were 6 combinations of chronic diseases with strong association strengths and 14 with moderate association strengths. The results of the ARM were similar to the network analysis; six dyadic chronic disease combinations and six triadic ones were obtained. Hierarchical multiple logistic regression indicated that innate personal traits (age, history of genetics, and body mass index), behavioral lifestyle (physical activity levels and medication adherence), interpersonal network (marital status), and socioeconomic status (educational level) were the common predictors of multimorbidity for older adults, among which, having no family history was found to be a relative determinant as a protective factor for multimorbidity after controlling the other covariates. (4) Conclusions: multimorbidity was prevalent in older adults and most disease combinations are associated with hypertension, followed by diabetes. This shows that diabetes and hypertension have a high prevalence among older adults and have a wide range of associations with other chronic diseases. Exploring the patterns and associated factors of multimorbidity will help the country prevent complications and avoid the unnecessary use of the health service, adopting an integrated approach to managing multimorbidity rather than an individual disease-specific approach and implementing different strategies according to the location of residence.
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spelling pubmed-97793692022-12-23 Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective Chen, Yiming Shi, Lei Zheng, Xiao Yang, Juan Xue, Yaqing Xiao, Shujuan Xue, Benli Zhang, Jiachi Li, Xinru Lin, Huang Ma, Chao Zhang, Chichen Int J Environ Res Public Health Article (1) Background: Multimorbidity has become one of the key issues in the public health sector. This study aims to explore the patterns and health-ecological factors of multimorbidity in China to propose policy recommendations for the management of chronic diseases in the elderly. (2) Methods: A multi-stage random sampling method was used to conduct a questionnaire survey on 3637 older adults aged 60 and older in Shanxi, China. Association rule mining analysis (ARM) and network analysis were applied to analyze the patterns of multimorbidity. The health-ecological model was adopted to explore the potential associated factors of multimorbidity in a multidimensional perspective. A hierarchical multiple logistic model was employed to investigate the association strengths reflected by adjusted odds ratios and 95% confidence. (3) Results: Multimorbidity occurred in 20.95% of the respondents. The graph of network analysis showed that there were 6 combinations of chronic diseases with strong association strengths and 14 with moderate association strengths. The results of the ARM were similar to the network analysis; six dyadic chronic disease combinations and six triadic ones were obtained. Hierarchical multiple logistic regression indicated that innate personal traits (age, history of genetics, and body mass index), behavioral lifestyle (physical activity levels and medication adherence), interpersonal network (marital status), and socioeconomic status (educational level) were the common predictors of multimorbidity for older adults, among which, having no family history was found to be a relative determinant as a protective factor for multimorbidity after controlling the other covariates. (4) Conclusions: multimorbidity was prevalent in older adults and most disease combinations are associated with hypertension, followed by diabetes. This shows that diabetes and hypertension have a high prevalence among older adults and have a wide range of associations with other chronic diseases. Exploring the patterns and associated factors of multimorbidity will help the country prevent complications and avoid the unnecessary use of the health service, adopting an integrated approach to managing multimorbidity rather than an individual disease-specific approach and implementing different strategies according to the location of residence. MDPI 2022-12-14 /pmc/articles/PMC9779369/ /pubmed/36554647 http://dx.doi.org/10.3390/ijerph192416756 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Yiming
Shi, Lei
Zheng, Xiao
Yang, Juan
Xue, Yaqing
Xiao, Shujuan
Xue, Benli
Zhang, Jiachi
Li, Xinru
Lin, Huang
Ma, Chao
Zhang, Chichen
Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title_full Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title_fullStr Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title_full_unstemmed Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title_short Patterns and Determinants of Multimorbidity in Older Adults: Study in Health-Ecological Perspective
title_sort patterns and determinants of multimorbidity in older adults: study in health-ecological perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779369/
https://www.ncbi.nlm.nih.gov/pubmed/36554647
http://dx.doi.org/10.3390/ijerph192416756
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