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Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure—Function Relationships

DNA helicase unwinding activity can be inhibited by small molecules and by covalently bound DNA lesions. Little is known about the relationships between the structural features of DNA lesions and their impact on unwinding rates and processivities. Employing E.coli RecQ helicase as a model system, an...

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Detalles Bibliográficos
Autores principales:	Sales, Ana H., Zheng, Vincent, Kenawy, Maya A., Kakembo, Mark, Zhang, Lu, Shafirovich, Vladimir, Broyde, Suse, Geacintov, Nicholas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779537/ https://www.ncbi.nlm.nih.gov/pubmed/36555294 http://dx.doi.org/10.3390/ijms232415654

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