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PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells
Triple-negative breast cancer is more aggressive than other types of breast cancer. Protein kinase R (PKR), which is activated by dsRNA, is known to play a role in doxorubicin-mediated apoptosis; however, its role in DNA damage-mediated apoptosis is not well understood. In this study, we investigate...
Autores principales: | Lee, Sol, Jee, Ha-Yeon, Lee, Yoon-Gyeong, Shin, Jong-Il, Jeon, Yong-Joon, Kim, Ji-Beom, Seo, Hye-eun, Lee, Ji-Yeon, Lee, Kyungho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779813/ https://www.ncbi.nlm.nih.gov/pubmed/36555509 http://dx.doi.org/10.3390/ijms232415872 |
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