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PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells

Triple-negative breast cancer is more aggressive than other types of breast cancer. Protein kinase R (PKR), which is activated by dsRNA, is known to play a role in doxorubicin-mediated apoptosis; however, its role in DNA damage-mediated apoptosis is not well understood. In this study, we investigate...

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Detalles Bibliográficos
Autores principales:	Lee, Sol, Jee, Ha-Yeon, Lee, Yoon-Gyeong, Shin, Jong-Il, Jeon, Yong-Joon, Kim, Ji-Beom, Seo, Hye-eun, Lee, Ji-Yeon, Lee, Kyungho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779813/ https://www.ncbi.nlm.nih.gov/pubmed/36555509 http://dx.doi.org/10.3390/ijms232415872

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