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Butyrate Lowers Cellular Cholesterol through HDAC Inhibition and Impaired SREBP-2 Signalling
In animal studies, HDAC inhibitors such as butyrate have been reported to reduce plasma cholesterol, while conferring protection from diabetes, but studies on the underlying mechanisms are lacking. This study compares the influence of butyrate and other HDAC inhibitors to that of statins on choleste...
Autores principales: | Bridgeman, Stephanie, Woo, Hon Chiu, Newsholme, Philip, Mamotte, Cyril |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779842/ https://www.ncbi.nlm.nih.gov/pubmed/36555149 http://dx.doi.org/10.3390/ijms232415506 |
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