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Exacerbation of Cisplatin Cellular Toxicity by Regulation of the Human Organic Cation Transporter 2 through Angiotensin II

Cisplatin (CDDP) is an efficient chemotherapeutic drug, whose use is associated with the development of serious undesired toxicities, such as nephrotoxicity. The human organic cation transporter 2 (hOCT2), which is highly expressed in the basolateral membrane domain of renal proximal tubules seems t...

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Detalles Bibliográficos
Autores principales: Kantauskaite, Marta, Hucke, Anna, Snieder, Beatrice, Ciarimboli, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779897/
https://www.ncbi.nlm.nih.gov/pubmed/36555515
http://dx.doi.org/10.3390/ijms232415866