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Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years
OBJECTIVE: The aim of this study was to investigate the effectiveness of immature granulocyte count, immature granulocyte percentage, and total bilirubin value in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. METHODS: In this...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Médica Brasileira
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779967/ https://www.ncbi.nlm.nih.gov/pubmed/36449794 http://dx.doi.org/10.1590/1806-9282.20220729 |
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author | Altiner, Saygın Cebeci, Enes Sucu, Bedri Burak Col, Mert Ermiş, İlker Senlikci, Abdullah Ünal, Yılmaz Pekcici, Mevlut Recep |
author_facet | Altiner, Saygın Cebeci, Enes Sucu, Bedri Burak Col, Mert Ermiş, İlker Senlikci, Abdullah Ünal, Yılmaz Pekcici, Mevlut Recep |
author_sort | Altiner, Saygın |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to investigate the effectiveness of immature granulocyte count, immature granulocyte percentage, and total bilirubin value in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. METHODS: In this study, 84 patients, aged 65 years and older, who had appendectomy demographic information, preoperative white blood cell count, neutrophil/lymphocyte ratio, immature granulocyte count and immature granulocyte percentage, operation findings, and pathology results were collected retrospectively. They were grouped into 4 categories: complicated, non-complicated, perforated, and non-perforated, according to the data and surgical findings. RESULTS: Total bilirubin and immature granulocyte count were found to be statistically significant in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. The total bilirubin was found to have the following values in differentiating complicated appendicitis: area under the curve=0.883, sensitivity=78.3%, and specificity=88.5%. Total bilirubin had the highest discrimination power with area under the curve=0.804 in differentiating perforation. CONCLUSION: The immature granulocyte percentage and total bilirubin count are the fast, inexpensive, and reliable parameters that can be used to predict complicated and perforated appendicitis in patients aged 65 years and older. |
format | Online Article Text |
id | pubmed-9779967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Associação Médica Brasileira |
record_format | MEDLINE/PubMed |
spelling | pubmed-97799672022-12-23 Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years Altiner, Saygın Cebeci, Enes Sucu, Bedri Burak Col, Mert Ermiş, İlker Senlikci, Abdullah Ünal, Yılmaz Pekcici, Mevlut Recep Rev Assoc Med Bras (1992) Original Article OBJECTIVE: The aim of this study was to investigate the effectiveness of immature granulocyte count, immature granulocyte percentage, and total bilirubin value in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. METHODS: In this study, 84 patients, aged 65 years and older, who had appendectomy demographic information, preoperative white blood cell count, neutrophil/lymphocyte ratio, immature granulocyte count and immature granulocyte percentage, operation findings, and pathology results were collected retrospectively. They were grouped into 4 categories: complicated, non-complicated, perforated, and non-perforated, according to the data and surgical findings. RESULTS: Total bilirubin and immature granulocyte count were found to be statistically significant in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. The total bilirubin was found to have the following values in differentiating complicated appendicitis: area under the curve=0.883, sensitivity=78.3%, and specificity=88.5%. Total bilirubin had the highest discrimination power with area under the curve=0.804 in differentiating perforation. CONCLUSION: The immature granulocyte percentage and total bilirubin count are the fast, inexpensive, and reliable parameters that can be used to predict complicated and perforated appendicitis in patients aged 65 years and older. Associação Médica Brasileira 2022-11-25 /pmc/articles/PMC9779967/ /pubmed/36449794 http://dx.doi.org/10.1590/1806-9282.20220729 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Altiner, Saygın Cebeci, Enes Sucu, Bedri Burak Col, Mert Ermiş, İlker Senlikci, Abdullah Ünal, Yılmaz Pekcici, Mevlut Recep Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title | Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title_full | Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title_fullStr | Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title_full_unstemmed | Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title_short | Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
title_sort | role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779967/ https://www.ncbi.nlm.nih.gov/pubmed/36449794 http://dx.doi.org/10.1590/1806-9282.20220729 |
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