4-Hydroxyisoleucine inhibits tumor growth by triggering endoplasmic reticulum stress and autophagy

4-Hydroxyisoleucine（4-HIL）is a non-protein amino acid that is able to reduce obesity and improve insulin sensitivity in mice, and recently emerged as a drug candidate against hypoglycemia. For the first time, we found that 4-HIL exhibits a potent anti-tumor activity in various cancer cell lines in v...

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Detalles Bibliográficos
Autores principales: Li, Peng, Yang, Yonghui, Qiu, Lu, Wan, Guangming, Yuan, Baomei, Wu, Yahong, Gao, Yanfeng, Li, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780060/
https://www.ncbi.nlm.nih.gov/pubmed/36568272
http://dx.doi.org/10.1016/j.crphar.2022.100127

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