Reconstructing Complex Cancer Evolutionary Histories from Multiple Bulk DNA Samples Using Pairtree

Cancers are composed of genetically distinct subpopulations of malignant cells. DNA-sequencing data can be used to determine the somatic point mutations specific to each population and build clone trees describing the evolutionary relationships between them. These clone trees can reveal critical poi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wintersinger, Jeff A., Dobson, Stephanie M., Kulman, Ethan, Stein, Lincoln D., Dick, John E., Morris, Quaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780082/
https://www.ncbi.nlm.nih.gov/pubmed/35247876
http://dx.doi.org/10.1158/2643-3230.BCD-21-0092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780082/
https://www.ncbi.nlm.nih.gov/pubmed/35247876
http://dx.doi.org/10.1158/2643-3230.BCD-21-0092

Ejemplares similares