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Microdialysis of Voriconazole and its N-Oxide Metabolite: Amalgamating Knowledge of Distribution and Metabolism Processes in Humans

PURPOSE: Voriconazole is an essential antifungal drug whose complex pharmacokinetics with high interindividual variability impedes effective and safe therapy. By application of the minimally-invasive sampling technique microdialysis, interstitial space fluid (ISF) concentrations of VRC and its poten...

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Detalles Bibliográficos
Autores principales:	Schulz, Josefine, Michelet, Robin, Zeitlinger, Markus, Mikus, Gerd, Kloft, Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780129/ https://www.ncbi.nlm.nih.gov/pubmed/36271205 http://dx.doi.org/10.1007/s11095-022-03407-7

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