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Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics

PURPOSE: Quantification of pharmacodynamic interactions is key in combination therapies, yet conventional checkerboard experiments with up to 10 by 10 combinations are labor-intensive. Therefore, this study provides optimized experimental rhombic checkerboard designs to enable an efficient interacti...

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Detalles Bibliográficos
Autores principales:	Kroemer, Niklas, Aubry, Romain, Couet, William, Grégoire, Nicolas, Wicha, Sebastian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780134/ https://www.ncbi.nlm.nih.gov/pubmed/36163408 http://dx.doi.org/10.1007/s11095-022-03396-7

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