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Exon junction complex shapes the m(6)A epitranscriptome

N6-methyladenosine (m(6)A), the most abundant modification of mRNA, is essential for normal development and dysregulation promotes cancer. m(6)A is highly enriched in the 3’ untranslated region (UTR) of a large subset of mRNAs to influence mRNA stability and/or translation. However, the mechanism re...

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Detalles Bibliográficos
Autores principales: Yang, Xin, Triboulet, Robinson, Liu, Qi, Sendinc, Erdem, Gregory, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780246/
https://www.ncbi.nlm.nih.gov/pubmed/36550132
http://dx.doi.org/10.1038/s41467-022-35643-1