Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing

The infection of Nocardia gipuzkoensis is a relatively uncommon form of pulmonary nocardiosis seen in clinical patients. In general, nocardiosis tends to occur in patients with immune deficiency. Here, we report a 23-year-old female who was admitted to the hospital due to cough and sputum production...

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Autores principales: Liu, Chengxin, Yang, Juhua, Huang, Huiting, Zhan, Shaofeng, Xia, Xintian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780257/
https://www.ncbi.nlm.nih.gov/pubmed/36569853
http://dx.doi.org/10.3389/fimmu.2022.1053914
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author Liu, Chengxin
Yang, Juhua
Huang, Huiting
Zhan, Shaofeng
Xia, Xintian
author_facet Liu, Chengxin
Yang, Juhua
Huang, Huiting
Zhan, Shaofeng
Xia, Xintian
author_sort Liu, Chengxin
collection PubMed
description The infection of Nocardia gipuzkoensis is a relatively uncommon form of pulmonary nocardiosis seen in clinical patients. In general, nocardiosis tends to occur in patients with immune deficiency. Here, we report a 23-year-old female who was admitted to the hospital due to cough and sputum production over 10 years, diagnosed with bronchiectasis. The N. gipuzkoensis infection was identified by metagenomic next-generation sequencing and whole genome sequencing. Imipenem/cilastatin and compound sulfamethoxazole tablets were used to control the infection and the pulmonary inflammation subsided gradually.
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spelling pubmed-97802572022-12-24 Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing Liu, Chengxin Yang, Juhua Huang, Huiting Zhan, Shaofeng Xia, Xintian Front Immunol Immunology The infection of Nocardia gipuzkoensis is a relatively uncommon form of pulmonary nocardiosis seen in clinical patients. In general, nocardiosis tends to occur in patients with immune deficiency. Here, we report a 23-year-old female who was admitted to the hospital due to cough and sputum production over 10 years, diagnosed with bronchiectasis. The N. gipuzkoensis infection was identified by metagenomic next-generation sequencing and whole genome sequencing. Imipenem/cilastatin and compound sulfamethoxazole tablets were used to control the infection and the pulmonary inflammation subsided gradually. Frontiers Media S.A. 2022-12-09 /pmc/articles/PMC9780257/ /pubmed/36569853 http://dx.doi.org/10.3389/fimmu.2022.1053914 Text en Copyright © 2022 Liu, Yang, Huang, Zhan and Xia https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Liu, Chengxin
Yang, Juhua
Huang, Huiting
Zhan, Shaofeng
Xia, Xintian
Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title_full Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title_fullStr Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title_full_unstemmed Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title_short Case report: Nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
title_sort case report: nocardia gipuzkoensis infection in an immunocompetent patient diagnosed by metagenomic next-generation sequencing and whole genome sequencing
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780257/
https://www.ncbi.nlm.nih.gov/pubmed/36569853
http://dx.doi.org/10.3389/fimmu.2022.1053914
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