Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease

Type 1 diabetes affects over nine million individuals globally, with approximately 40% developing diabetic kidney disease. Emerging evidence suggests that epigenetic alterations, such as DNA methylation, are involved in diabetic kidney disease. Here we assess differences in blood-derived genome-wide...

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Detalles Bibliográficos
Autores principales: Smyth, Laura J., Dahlström, Emma H., Syreeni, Anna, Kerr, Katie, Kilner, Jill, Doyle, Ross, Brennan, Eoin, Nair, Viji, Fermin, Damian, Nelson, Robert G., Looker, Helen C., Wooster, Christopher, Andrews, Darrell, Anderson, Kerry, McKay, Gareth J., Cole, Joanne B., Salem, Rany M., Conlon, Peter J., Kretzler, Matthias, Hirschhorn, Joel N., Sadlier, Denise, Godson, Catherine, Florez, Jose C., Forsblom, Carol, Maxwell, Alexander P., Groop, Per-Henrik, Sandholm, Niina, McKnight, Amy Jayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780337/
https://www.ncbi.nlm.nih.gov/pubmed/36550108
http://dx.doi.org/10.1038/s41467-022-34963-6

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