Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasion

KDM5C is a histone H3K4-specific demethylase, which has been shown to play a key role in biological disease and development. However, the role of KDM5C in trophoblasts at early pregnancy is currently unknown. Here, we showed that KDM5C was upregulated in placental trophoblasts from recurrent miscarr...

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Detalles Bibliográficos
Autores principales: Xiao, Min, Zheng, Yan, Wang, Meng-Xi, Sun, Yi-Hua, Chen, Juan, Zhu, Kang-Yong, Zhang, Fan, Tang, Yun-Hui, Yang, Fan, Zhou, Ting, Zhang, Yue-Ping, Lei, Cai-Xia, Sun, Xiao-Xi, Yu, Shan-He, Tian, Fu-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780362/
https://www.ncbi.nlm.nih.gov/pubmed/36550096
http://dx.doi.org/10.1038/s41420-022-01284-y

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