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Bioavailability of dissolved and crushed single tablets of bictegravir, emtricitabine, tenofovir alafenamide in healthy adults: the SOLUBIC randomized crossover study

BACKGROUND: Crushing or dissolving bictegravir/tenofovir alafenamide/emtricitabine (BIC/TAF/FTC) tablets is not recommended because there are no data supporting this practice. METHODS: A crossover, randomized trial in healthy adults (NCT04244448) investigated the bioavailability of two off-label use...

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Detalles Bibliográficos
Autores principales:	Hocqueloux, Laurent, Lefeuvre, Sandrine, Bois, Julie, Brucato, Sylvie, Alix, Antoine, Valentin, Cécile, Peyro-Saint-Paul, Laure, Got, Laurence, Fournel, François, Dargere, Sylvie, Prazuck, Thierry, Fournier, Anna, Gregoire, Nicolas, McNicholl, Ian, Parienti, Jean-Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780524/ https://www.ncbi.nlm.nih.gov/pubmed/36322475 http://dx.doi.org/10.1093/jac/dkac369

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