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Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2. The full-length membrane form of ACE2 (memACE2) undergoes ectodomain shedding to generate a shed soluble form (solACE2) that mediates...
Autores principales: | Guo, Xuanming, Cao, Jianli, Cai, Jian-Piao, Wu, Jiayan, Huang, Jiangang, Asthana, Pallavi, Wong, Sheung Kin Ken, Ye, Zi-Wei, Gurung, Susma, Zhang, Yijing, Wang, Sheng, Wang, Zening, Ge, Xin, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Wong, Nathalie, Huang, Jiandong, Zhou, Zhongjun, Bian, Zhao-Xiang, Yuan, Shuofeng, Wong, Hoi Leong Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780620/ https://www.ncbi.nlm.nih.gov/pubmed/36564389 http://dx.doi.org/10.1038/s41467-022-35590-x |
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