Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial

OBJECTIVES: C-C-chemokine receptors (CCRs) are expressed on a variety of immune cells and play an important role in many immune processes, particularly leukocyte migration. Comprehensive preclinical research demonstrated CCR2/CCR5-dependent pathways as pivotal for the pathophysiology of severe COVID...

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Detalles Bibliográficos
Autores principales: Kurth, Florian, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Barbone, Gianluca, Eckart, Marius A., Kluge, Martin, Puengel, Tobias, Demir, Münevver, Röhle, Robert, Keller, Theresa, Ruwwe-Glösenkamp, Christoph, Witzenrath, Martin, Suttorp, Norbert, von Kalle, Christof, Sander, Leif E., Jochum, Christoph, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy. 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780636/
https://www.ncbi.nlm.nih.gov/pubmed/36572146
http://dx.doi.org/10.1016/j.jgar.2022.12.004

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