Bifunctional Peptidomimetic G Protein-Biased Mu-Opioid Receptor Agonist and Neuropeptide FF Receptor Antagonist KGFF09 Shows Efficacy in Visceral Pain without Rewarding Effects after Subcutaneous Administration in Mice

There is still an unmet clinical need to develop new pharmaceuticals for effective and safe pain management. Current pharmacotherapy offers unsatisfactory solutions due to serious side effects related to the chronic use of opioid drugs. Prescription opioids produce analgesia through activation of th...

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Detalles Bibliográficos
Autores principales: Dumitrascuta, Maria, Martin, Charlotte, Ballet, Steven, Spetea, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780937/
https://www.ncbi.nlm.nih.gov/pubmed/36557917
http://dx.doi.org/10.3390/molecules27248785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9780937/
https://www.ncbi.nlm.nih.gov/pubmed/36557917
http://dx.doi.org/10.3390/molecules27248785

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